Abstract
Glioblastoma multiforme represents one of the most aggressive tumor of central nervous system. Current therapy includes surgery, radiation and chemotherapy. These treatments are rarely curative and glioma are associated with a poor prognosis. Nanomedicine represents the most innovative branch of medicine since many studies demonstrated great advantage in the diagnosis and therapy of several diseases. In this review we will summarize the results obtained by the use of nanoparticles and extracellular vesicles in glioblastoma. A great interest is raising from these studies that underlined the efficacy and specificity of this treatment for glioma, reducing side-effects associated with conventional therapies.
Keywords: Glioblastoma, nanomedicine, nanoparticles, extracellular vesicles.
Current Cancer Drug Targets
Title:New Perspectives in Glioblastoma: Nanoparticles-based Approaches
Volume: 17 Issue: 3
Author(s): Rosa Luciano, Giulia Battafarano, Rossana Saracino, Michela Rossi, Antonio Perrotta, Melania Manco, Maurizio Muraca and Andrea Del Fattore
Affiliation:
Keywords: Glioblastoma, nanomedicine, nanoparticles, extracellular vesicles.
Abstract: Glioblastoma multiforme represents one of the most aggressive tumor of central nervous system. Current therapy includes surgery, radiation and chemotherapy. These treatments are rarely curative and glioma are associated with a poor prognosis. Nanomedicine represents the most innovative branch of medicine since many studies demonstrated great advantage in the diagnosis and therapy of several diseases. In this review we will summarize the results obtained by the use of nanoparticles and extracellular vesicles in glioblastoma. A great interest is raising from these studies that underlined the efficacy and specificity of this treatment for glioma, reducing side-effects associated with conventional therapies.
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Cite this article as:
Luciano Rosa, Battafarano Giulia, Saracino Rossana, Rossi Michela, Perrotta Antonio, Manco Melania, Muraca Maurizio and Fattore Del Andrea, New Perspectives in Glioblastoma: Nanoparticles-based Approaches, Current Cancer Drug Targets 2017; 17 (3) . https://dx.doi.org/10.2174/1568009616666160813190732
DOI https://dx.doi.org/10.2174/1568009616666160813190732 |
Print ISSN 1568-0096 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-5576 |
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