Abstract
Background: Acute pancreatitis (AP) is an inflammation process that can affect the systemic inflammatory response syndrome, mainly in obese individuals. The passion fruit peel flour (PFPF) is rich in fibers that help to reduce cholesterol and blood glucose levels.
Methods: In this study, AP was induced by 5% sodium taurocholate inoculation (biliopancreatic duct). The prognosis was evaluated after treatment with PFPF in obese rats overfed during lactation. PFPF (40 mg/kg b.w.) was administered by oral gavage five h after AP induction or sham surgery. Wistar rats were divided into 6 groups: control; sham (CSP), AP (CP) and AP treated with PFPF (40mg) (CP40); obese, sham (OSP), AP (OP), and AP treated with PFPF (40mg) (OP40).
Results: The results demonstrated a significant reduction of blood glucose and triglyceride concentrations after PFPF treatment, compared to AP groups. PFPF treated groups also had lower concentrations of IL-6, and an increased concentration of IL-10 in the OP40 group.
Conclusion: In conclusion, PFPF delays the absorption of simple carbohydrates, due to being rich in pectin (in gel form). This improved glycemic control after AP induction. This may be useful in improving the inflammatory response during acute pancreatitis.
Keywords: Acute pancreatitis, blood, glucose, glycemic control, inflammatory response, obesity, overnutrition, passion fruit peel flour, triglyceride.
The Natural Products Journal
Title:Effect of Passion Fruit (Passiflora edulis f. flavicarpa deg.) Peel Flour on the Prognosis of Acute Pancreatitis after Overnutrition During Lactation
Volume: 6 Issue: 3
Author(s): Glauciane Lacerda-Miranda, Vivian M. Soares, Alessandra A. Thole, Erika Cortez, Lais Carvalho, Carlos E.R. Caetano, Erica P.G. Souza, Anibal S. Moura, Ruy G. Marques, Armando U.O. Sabaa-Srur and Robert E. Smith
Affiliation:
Keywords: Acute pancreatitis, blood, glucose, glycemic control, inflammatory response, obesity, overnutrition, passion fruit peel flour, triglyceride.
Abstract: Background: Acute pancreatitis (AP) is an inflammation process that can affect the systemic inflammatory response syndrome, mainly in obese individuals. The passion fruit peel flour (PFPF) is rich in fibers that help to reduce cholesterol and blood glucose levels.
Methods: In this study, AP was induced by 5% sodium taurocholate inoculation (biliopancreatic duct). The prognosis was evaluated after treatment with PFPF in obese rats overfed during lactation. PFPF (40 mg/kg b.w.) was administered by oral gavage five h after AP induction or sham surgery. Wistar rats were divided into 6 groups: control; sham (CSP), AP (CP) and AP treated with PFPF (40mg) (CP40); obese, sham (OSP), AP (OP), and AP treated with PFPF (40mg) (OP40).
Results: The results demonstrated a significant reduction of blood glucose and triglyceride concentrations after PFPF treatment, compared to AP groups. PFPF treated groups also had lower concentrations of IL-6, and an increased concentration of IL-10 in the OP40 group.
Conclusion: In conclusion, PFPF delays the absorption of simple carbohydrates, due to being rich in pectin (in gel form). This improved glycemic control after AP induction. This may be useful in improving the inflammatory response during acute pancreatitis.
Export Options
About this article
Cite this article as:
Lacerda-Miranda Glauciane, Soares M. Vivian, Thole A. Alessandra, Cortez Erika, Carvalho Lais, Caetano E.R. Carlos, Souza P.G. Erica, Moura S. Anibal, Marques G. Ruy, Sabaa-Srur U.O. Armando and Smith E. Robert, Effect of Passion Fruit (Passiflora edulis f. flavicarpa deg.) Peel Flour on the Prognosis of Acute Pancreatitis after Overnutrition During Lactation, The Natural Products Journal 2016; 6 (3) . https://dx.doi.org/10.2174/2210315506666160725154815
DOI https://dx.doi.org/10.2174/2210315506666160725154815 |
Print ISSN 2210-3155 |
Publisher Name Bentham Science Publisher |
Online ISSN 2210-3163 |
Call for Papers in Thematic Issues
Ayurvedic medicinal therapeutic approaches for inflammatory and neurodegenerative disorders
Usually, in our elderly population, neurodegenerative disorders occur due to neuron death. Alzheimer?s disease (AD) is an irreversible and progressive neurodegenerative disease. Dementia is the leading cause of AD, which affects about 30 million people worldwide. According to the World Alzheimer report 2018, a new case of dementia develops every ...read more
Recent Advances in Biotransformation of Bioactive Terpenoids using Aspergillus niger
Biotransformation is the reaction catalyzed by biological catalysts of either isolated enzymes or whole cell cultures of microorganisms. This process has been extensively applied in the conversion of bioactive terpenoids with high regio- and stereospecifity. This process has been also applied in the lead discovery and development. Aspergillus niger has ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Autoimmune Polyendocrine Syndrome Complicated by Pulmonary Hypertension
Endocrine, Metabolic & Immune Disorders - Drug Targets Nanoparticles: A Promising Therapeutic Approach in Atherosclerosis
Current Drug Delivery Recent Advances on the Role of microRNAs in both Insulin Resistance and Cancer
Current Pharmaceutical Design Hypertension: Basics Concepts and the Evolving Role of Novel Treatments
Current Hypertension Reviews Diagnosis and New Approaches in the Therapy of Gestational Diabetes Mellitus
Current Diabetes Reviews Emerging Trends On Drug Delivery Strategy of Momordica charantia against Diabetes and its Complications
Current Drug Delivery Design, Synthesis, and Structure-Activity Relationship Study of Peroxisome Proliferator-Activated Receptor (PPAR) δ-Selective Ligands
Current Medicinal Chemistry Ocular Vascular Involvement in the Rheumatic Diseases
Current Rheumatology Reviews Anti-Apoptotic Effect of Human Telomerase Reverse Transcriptase on Endothelial Cells under Oxidative Stress, Independent of Telomere Elongation and Telomerase Activity
Immunology, Endocrine & Metabolic Agents in Medicinal Chemistry (Discontinued) Engagement of Renin-Angiotensin System in Prostate Cancer
Current Cancer Drug Targets Pathophysiology of Cardiovascular Diseases and the Role of Vitamins, and Herbal Extracts in the Reduction of Cardiovascular Risks
Cardiovascular & Hematological Agents in Medicinal Chemistry Syntheses and Biological Activities of triazole-based Sulfonamides
Current Organic Chemistry The Role of Myocardial Collagen Network in Hypertensive Heart Disease
Current Hypertension Reviews The Novel Functions of cGMP-Specific Phosphodiesterase 5 and its Inhibitors in Carcinoma Cells and Pulmonary/Cardiovascular Vessels
Current Topics in Medicinal Chemistry The Fetal Cardiac Function
Current Cardiology Reviews Lipoprotein (a) and Cardiovascular Risk: The Show Must go on
Current Medicinal Chemistry Non-Communicable Diseases and Adherence to Mediterranean Diet
Endocrine, Metabolic & Immune Disorders - Drug Targets Predictive Factors of Febrile Neutropenia Induced by Anticancer Chemotherapy in the South of Tunisia
Reviews on Recent Clinical Trials A Review of the Evidence for a Neuroendocrine Link Between Stress, Depression and Diabetes Mellitus
Current Diabetes Reviews Molecular Damage in Glaucoma: from Anterior to Posterior Eye Segment. The MicroRNA Role
MicroRNA