Abstract
The use of natural products for the treatment of disease is one of the oldest cultures exists. Currently, the research of new drugs using natural products shows a poorly explored biodiversity and a great interest of marketing. The enzymatic inhibition by some natural products is investigated among these is the inhibition of hyaluronidase and the consequent reduction of the degradation of hyaluronic acid. So there is a reduction of inflammation and angiogenesis. This study reports the main natural species studied in inhibiting human hyaluronidase that can be the subject of future research for new drugs.
Keywords: Enzyme, inhibition, hyaluronidase, natural products, inflammation, angiogenesis.
Current Topics in Medicinal Chemistry
Title:Recent Advancement in Natural Hyaluronidase Inhibitors
Volume: 16 Issue: 23
Author(s): Luciana Scotti, Rajeev Kumar Singla, Hamilton Mitsugu Ishiki, Francisco Jaime B. Mendonca, Marcelo Sobral da Silva, José Maria Barbosa Filho and Marcus Tullius Scotti
Affiliation:
Keywords: Enzyme, inhibition, hyaluronidase, natural products, inflammation, angiogenesis.
Abstract: The use of natural products for the treatment of disease is one of the oldest cultures exists. Currently, the research of new drugs using natural products shows a poorly explored biodiversity and a great interest of marketing. The enzymatic inhibition by some natural products is investigated among these is the inhibition of hyaluronidase and the consequent reduction of the degradation of hyaluronic acid. So there is a reduction of inflammation and angiogenesis. This study reports the main natural species studied in inhibiting human hyaluronidase that can be the subject of future research for new drugs.
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Cite this article as:
Scotti Luciana, Singla Kumar Rajeev, Ishiki Mitsugu Hamilton, Mendonca Jaime B. Francisco, da Silva Sobral Marcelo, Barbosa Filho Maria José and Scotti Tullius Marcus, Recent Advancement in Natural Hyaluronidase Inhibitors, Current Topics in Medicinal Chemistry 2016; 16 (23) . https://dx.doi.org/10.2174/1568026616666160414123857
DOI https://dx.doi.org/10.2174/1568026616666160414123857 |
Print ISSN 1568-0266 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4294 |
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