Abstract
Cardiovascular disease (CVD) remains a major cause of death and disability worldwide, thus preventing and inhibiting CVD remains a health priority. Several lines of pharmacological interventions have not met with great success, thus inhibition of novel cellular stress pathways could be a novel therapeutic avenue to treat CVD. This review will focus on homocysteine and endoplasmic reticulum stress linked to mitochondria function, and possible therapeutic avenues for treatment.
Keywords: Endoplasmic reticulum stress, endothelial function, homocysteine, atherosclerosis, taurine, Nox.
Current Pharmaceutical Design
Title:Endoplasmic Stress Inhibitors for Homocysteine Induced Cardiovascular Disease
Volume: 22 Issue: 18
Author(s): Anthony Zulli
Affiliation:
Keywords: Endoplasmic reticulum stress, endothelial function, homocysteine, atherosclerosis, taurine, Nox.
Abstract: Cardiovascular disease (CVD) remains a major cause of death and disability worldwide, thus preventing and inhibiting CVD remains a health priority. Several lines of pharmacological interventions have not met with great success, thus inhibition of novel cellular stress pathways could be a novel therapeutic avenue to treat CVD. This review will focus on homocysteine and endoplasmic reticulum stress linked to mitochondria function, and possible therapeutic avenues for treatment.
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Cite this article as:
Zulli Anthony, Endoplasmic Stress Inhibitors for Homocysteine Induced Cardiovascular Disease, Current Pharmaceutical Design 2016; 22 (18) . https://dx.doi.org/10.2174/1381612822666160406121342
DOI https://dx.doi.org/10.2174/1381612822666160406121342 |
Print ISSN 1381-6128 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4286 |
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