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Current Organic Chemistry

Editor-in-Chief

ISSN (Print): 1385-2728
ISSN (Online): 1875-5348

Cyclobutanones as Useful Synthons for the Preparation of Bioactive Molecules and Fused-Ring Chemicals

Author(s): Xiuyun Sun, Yonghui Sun and Yu Rao

Volume 20, Issue 18, 2016

Page: [1878 - 1901] Pages: 24

DOI: 10.2174/1385272820666160331235519

Price: $65

Abstract

Cyclobutanones are highly valuable intermediates in organic synthesis. They demonstrate interesting and rich reactivity in different types of reactions due to their strain energy. Under the lewis acid and transition-metal catalysis, cyclobutanones can serve as useful synthons for the preparation of a variety of bioactive molecules and fused-ring chemicals.

Keywords: Cyclobutanones, C-C bond activation, heterocycles, bioactive molecules.


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