Abstract
Background: The use of nanobiomaterials is increasing each day. Among the immense variety of nanomaterials developed and studied the hydroxyapatite is one of the most ones.
Objective: In this study we developed and tested nano-hydroxyapatite dopped with Ho-166 for bone cancer. Results: The results showed that the nano-hydroxyapatite dopped with Ho-166 has a great affinity for the bone. Conclusion: The pre-clinical studies support the use as a nano-radiopharmaceuticals for bone cancer treatment and diagnosis.Keywords: Radiopharmaceuticals, nanotechnology, oncology, scanning electron microscopy, transmission electron microscopy.
Anti-Cancer Agents in Medicinal Chemistry
Title:Nano-Hydroxyapatite Doped with Ho-166 as Drug Delivery System for Bone Cancer Therapy and Diagnosis: Developing a Theragnostic Radiopharmaceuticals
Volume: 17 Issue: 3
Author(s): Franciana Maria Rosa da Silva, Julio Cezar de Almeida, Elizabeth Eugenio de Mello Oliveira, Marta de Souza Albernaz, Alexandre Malta Rossi and Ralph Santos-Oliveira
Affiliation:
Keywords: Radiopharmaceuticals, nanotechnology, oncology, scanning electron microscopy, transmission electron microscopy.
Abstract: Background: The use of nanobiomaterials is increasing each day. Among the immense variety of nanomaterials developed and studied the hydroxyapatite is one of the most ones.
Objective: In this study we developed and tested nano-hydroxyapatite dopped with Ho-166 for bone cancer. Results: The results showed that the nano-hydroxyapatite dopped with Ho-166 has a great affinity for the bone. Conclusion: The pre-clinical studies support the use as a nano-radiopharmaceuticals for bone cancer treatment and diagnosis.Export Options
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Cite this article as:
Silva Maria Rosa da Franciana, Almeida Cezar de Julio, Oliveira Eugenio de Mello Elizabeth, Albernaz de Souza Marta, Rossi Malta Alexandre and Santos-Oliveira Ralph, Nano-Hydroxyapatite Doped with Ho-166 as Drug Delivery System for Bone Cancer Therapy and Diagnosis: Developing a Theragnostic Radiopharmaceuticals, Anti-Cancer Agents in Medicinal Chemistry 2017; 17 (3) . https://dx.doi.org/10.2174/1871520616666151110130428
DOI https://dx.doi.org/10.2174/1871520616666151110130428 |
Print ISSN 1871-5206 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5992 |
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