Abstract
The incidence of gastric cancer is third most prevalent among all malignant tumors in China. The conventional therapies for advanced gastric cancer are futile. Targeted gene therapy has become a promising alternative approach. Mesenchymal stem cells (MSCs) can be used as potential cellular vehicles for cancer therapy in vivo. This review will summarize the published data about the application of MSC-based targeted therapy for gastric cancer, and discuss some of the challenges associated with this method.
Keywords: Challenges, conventional therapies, gastric cancer, mesenchymal stem cells, targeted gene therapy, vehicle.
Current Stem Cell Research & Therapy
Title:Application of Mesenchymal Stem Cells in the Targeted Gene Therapy for Gastric Cancer
Volume: 11 Issue: 5
Author(s): Ya-Li Zhou, Yu-Min Li and Wen-Ting He
Affiliation:
Keywords: Challenges, conventional therapies, gastric cancer, mesenchymal stem cells, targeted gene therapy, vehicle.
Abstract: The incidence of gastric cancer is third most prevalent among all malignant tumors in China. The conventional therapies for advanced gastric cancer are futile. Targeted gene therapy has become a promising alternative approach. Mesenchymal stem cells (MSCs) can be used as potential cellular vehicles for cancer therapy in vivo. This review will summarize the published data about the application of MSC-based targeted therapy for gastric cancer, and discuss some of the challenges associated with this method.
Export Options
About this article
Cite this article as:
Zhou Ya-Li, Li Yu-Min and He Wen-Ting, Application of Mesenchymal Stem Cells in the Targeted Gene Therapy for Gastric Cancer, Current Stem Cell Research & Therapy 2016; 11 (5) . https://dx.doi.org/10.2174/1574888X10666151026113818
DOI https://dx.doi.org/10.2174/1574888X10666151026113818 |
Print ISSN 1574-888X |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3946 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
UDP-Glucuronosyltransferases
Current Drug Metabolism Identification of Drug Targets in Helicobacter pylori by in silico Analysis : Possible Therapeutic Implications for Gastric cancer
Current Cancer Drug Targets Natural Small Molecules as Stabilizers and Activators of Cancer-Associated NQO1 Polymorphisms
Current Drug Targets The Discovery and Development of Drug Combinations for the Treatment of Various Diseases from Patent Literature (1980-Present)
Current Topics in Medicinal Chemistry Lung Defence Mechanisms and Their Potential Role in the Prevention of Ventilator Associated Pneumonia
Current Respiratory Medicine Reviews Immunotoxins and Other Conjugates: Pre-clinical Studies
Mini-Reviews in Medicinal Chemistry Repositioning of Drugs in Cardiometabolic Disorders: Importance and Current Scenario
Current Topics in Medicinal Chemistry Graphical Abstracts:
Current Nanoscience Drug Design Targeting the CXCR4/CXCR7/CXCL12 Pathway
Current Topics in Medicinal Chemistry Identification of New Targets for Therapy of Osteolytic Bone Disease in Multiple Myeloma
Current Drug Targets Calpain-Associated Proteolytic Regulation of the Stromal Microenvironment in Cancer
Current Pharmaceutical Design Novel Anti-inflammatory Drugs from Marine Microbes
The Natural Products Journal Molecular Link Mechanisms between Inflammation and Cancer
Current Pharmaceutical Design GPR40 Agonists for the Treatment of Type 2 Diabetes Mellitus: Benefits and Challenges
Current Drug Targets Food-derived Bioactive Peptides - Opportunities for Designing Future Foods
Current Pharmaceutical Design Protein-Protein Interactions: Recent Progress in the Development of Selective PDZ Inhibitors
Current Chemical Biology Contrast-enhanced Ultrasound for Liver Imaging: Recent Advances
Current Pharmaceutical Design Novel Patented Src Kinase Inhibitor
Current Medicinal Chemistry Preclinical Pharmacokinetics: An Approach Towards Safer and Efficacious Drugs
Current Drug Metabolism Vitamins B1, B2, B3 and B9 – Occurrence, Biosynthesis Pathways and Functions in Human Nutrition
Mini-Reviews in Medicinal Chemistry