Abstract
Neuroendocrine tumors (NETs) are relatively uncommon. They typically arise in the gastrointestinal tract and lungs, and their incidence seems to be rising. Most patients have advanced disease at the time of diagnosis and many more will relapse after surgery. There is thus a great need for improvements in therapy for advanced neuroendocrine tumors. This article reviews the current therapy for both pancreatic NETs and non-pancreatic gastrointestinal NETs, and discusses recent advances in NET management with an emphasis on targeted therapy.
Keywords: Carcinoid tumors, neuroendocrine tumors, targeted therapy, therapy.
Current Clinical Pharmacology
Title:Advances in Systemic Therapy for Gastroenteropancreatic Neuroendocrine Malignancies
Volume: 10 Issue: 4
Author(s): Thorvardur R. Halfdanarson and Jonathan R. Strosberg
Affiliation:
Keywords: Carcinoid tumors, neuroendocrine tumors, targeted therapy, therapy.
Abstract: Neuroendocrine tumors (NETs) are relatively uncommon. They typically arise in the gastrointestinal tract and lungs, and their incidence seems to be rising. Most patients have advanced disease at the time of diagnosis and many more will relapse after surgery. There is thus a great need for improvements in therapy for advanced neuroendocrine tumors. This article reviews the current therapy for both pancreatic NETs and non-pancreatic gastrointestinal NETs, and discusses recent advances in NET management with an emphasis on targeted therapy.
Export Options
About this article
Cite this article as:
Halfdanarson R. Thorvardur and Strosberg R. Jonathan, Advances in Systemic Therapy for Gastroenteropancreatic Neuroendocrine Malignancies, Current Clinical Pharmacology 2015; 10 (4) . https://dx.doi.org/10.2174/1574884710666151020100211
DOI https://dx.doi.org/10.2174/1574884710666151020100211 |
Print ISSN 1574-8847 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3938 |
Related Articles
-
Bile Acid Reabsorption Inhibitors (BARI): Novel Hypolipidemic Drugs
Current Medicinal Chemistry Subject Index To Volume 2
Current Psychiatry Reviews Role of Micronutrients on Subclinical Atherosclerosis Micronutrients in Subclinical Atherosclerosis
Current Pharmaceutical Design Role of Open Source Tools and Resources in Virtual Screening for Drug Discovery
Combinatorial Chemistry & High Throughput Screening Theoretical Possibilities for the Development of Novel Antiarrhythmic Drugs
Current Medicinal Chemistry Novel Risk Factors Related to Stable Angina
Current Pharmaceutical Design Role of Inflammatory Cells and Toll-Like Receptors in Atherosclerosis
Current Vascular Pharmacology Nitrogen and Sulfur Co-doped Fluorescent Carbon Dots for the Detection of Morin and Cell Imaging
Current Analytical Chemistry Cardiac Autonomic Nervous System in Heart Failure: Imaging Technique and Clinical Implications
Current Cardiology Reviews Effects of Dietary Coconut Oil on Erucic Acid Rich Rapeseed Oil-induced Changes of Blood Serum Lipids in Rats
Current Nutrition & Food Science Oxidative-Nitrosative Stress In Hypertension
Current Vascular Pharmacology Congenital Heart Disease: The Crossroads of Genetics, Epigenetics and Environment
Current Genomics Cardiac Calmodulin Kinase: A Potential Target for Drug Design
Current Medicinal Chemistry Aetiology, Diagnosis and Treatment of Hydrops Foetalis
Current Pediatric Reviews New Strategies and Drugs in the Treatment of Hypertension: Monotherapy or Combination?
Recent Patents on Cardiovascular Drug Discovery Cell Therapy for the Treatment of Chronic Ischemic Heart Disease
Current Pharmaceutical Design Platelets in Atherothrombosis: New and Evolving Roles
Current Pharmaceutical Design Vitamin D: A Pleiotropic Hormone with Possible Psychotropic Activities
Current Medicinal Chemistry Unequivocal Role of Pyrazine Ring in Medicinally Important Compounds: A Review
Mini-Reviews in Medicinal Chemistry Chromatographic Fingerprinting and Metabolomics for Quality Control of TCM
Combinatorial Chemistry & High Throughput Screening