Abstract
Liver fibrosis is an important cause of morbidity and mortality worldwide and represent a difficult clinical challenge of global importance. The liver fibrosis progression needs to be controlled because persisted liver fibrosis can lead to liver cirrhosis or even hepatocellular carcinoma. Despite significant advances in the understanding of the liver fibrosis development, the therapeutic effect of drugs used in liver fibrosis treatment is not sufficient. Today, nanotechnology has been considered as a potential tool for developing novel drug delivery systems for the improved imaging and various diseases, including liver fibrosis. In this article, we discussed the use of nanotechnology for the treatment and imaging of liver fibrosis.
Keywords: Antifibrotic therapy, antiviral therapy, hepatic stellate cells, liver fibrosis, nanotechnology, siRNA.
Current Drug Delivery
Title:Use of Nanotechnology in Diagnosis and Treatment of Hepatic Fibrosis: A Review
Volume: 13 Issue: 5
Author(s): Somayeh Taymouri and Azade Taheri
Affiliation:
Keywords: Antifibrotic therapy, antiviral therapy, hepatic stellate cells, liver fibrosis, nanotechnology, siRNA.
Abstract: Liver fibrosis is an important cause of morbidity and mortality worldwide and represent a difficult clinical challenge of global importance. The liver fibrosis progression needs to be controlled because persisted liver fibrosis can lead to liver cirrhosis or even hepatocellular carcinoma. Despite significant advances in the understanding of the liver fibrosis development, the therapeutic effect of drugs used in liver fibrosis treatment is not sufficient. Today, nanotechnology has been considered as a potential tool for developing novel drug delivery systems for the improved imaging and various diseases, including liver fibrosis. In this article, we discussed the use of nanotechnology for the treatment and imaging of liver fibrosis.
Export Options
About this article
Cite this article as:
Taymouri Somayeh and Taheri Azade, Use of Nanotechnology in Diagnosis and Treatment of Hepatic Fibrosis: A Review, Current Drug Delivery 2016; 13 (5) . https://dx.doi.org/10.2174/1567201812666150907115404
DOI https://dx.doi.org/10.2174/1567201812666150907115404 |
Print ISSN 1567-2018 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5704 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Antiphospholipid Antibody-Mediated Thrombotic Mechanisms in Antiphospholipid Syndrome: Towards Pathophysiology-Based Treatment
Current Pharmaceutical Design Role of Chitosan Biomaterials in Drug Delivery Systems: A Patent Perspective
Recent Patents on Materials Science Gene Transfer and Drug Delivery with Electric Pulse Generators
Current Drug Metabolism MicroRNAs in Breast Cancer Therapy
Current Pharmaceutical Design Thiopurines in Inflammatory Bowel Disease - The Role of Pharmacogenetics and Therapeutic Drug Monitoring
Current Pharmacogenomics Role of Phase II Drug Metabolizing Enzymes in Cancer Chemoprevention
Current Drug Metabolism General Principles for the Treatment of Non-Infectious Uveitis
Inflammation & Allergy - Drug Targets (Discontinued) Hemolytic Uremic Syndrome in Children
Current Pediatric Reviews Small-molecule Inhibitors of Epigenetic Mutations as Compelling Drugtargets for Myelodysplastic Syndromes
Current Cancer Drug Targets Role of Hsp70 in Cancer Growth and Survival
Protein & Peptide Letters Patient Radiation Doses in Interventional Cardiology Procedures
Current Cardiology Reviews Selective VEGFR Inhibitors for Anticancer Therapeutics in Clinical Use and Clinical Trials
Current Pharmaceutical Design Immunotherapy of Acute Myeloid Leukemia
Current Pharmaceutical Biotechnology Telomere Maintenance Mechanisms in Cancer: Clinical Implications
Current Pharmaceutical Design <i>Arctium Lappa</i> and Management of Liver Functions to Detoxify the Bloodstream
The Natural Products Journal Novel Approaches to Modulate Apoptosis Resistance: Basic and Clinical Implications in the Treatment of Chronic Lymphocytic Leukemia (CLL)
Current Drug Delivery Opportunities and Challenges in Nano-structure Mediated Drug Delivery: Where Do We Stand?
Current Nanomedicine Bugs as Drugs: Understanding the Linkage between Gut Microbiota and Cancer Treatment
Current Drug Targets Epidemiology and Prevention of Bacterial Infections in Patients with Hematologic Malignancies
Infectious Disorders - Drug Targets High-density Lipoprotein, Vascular Risk, Cancer and Infection: A Case of Quantity and Quality?
Current Medicinal Chemistry