Abstract
The reactions of sulfur ylides with carbonyl, olefin or imine compounds named as the Corey- Chaykovsky, provide oxiranes, cyclopropane or aziridine, respectively. In this report, we try to introduce this important name reaction and highlight a comprehensive overview on the applications of this useful reaction in synthetic organic chemistry and total synthesis of natural products.
Keywords: Corey-Chaykovsky, epoxidation, dimethylsulfoxonium methylide, dimethylsulfonium methylide, organic and total synthesis.
Current Organic Synthesis
Title:Developments of Corey-Chaykovsky in Organic Reactions and Total Synthesis of Natural Products
Volume: 13 Issue: 3
Author(s): Majid M. Heravi, Shima Asadi, Niousha Nazari and Boshra Malekzadeh Lashkariani
Affiliation:
Keywords: Corey-Chaykovsky, epoxidation, dimethylsulfoxonium methylide, dimethylsulfonium methylide, organic and total synthesis.
Abstract: The reactions of sulfur ylides with carbonyl, olefin or imine compounds named as the Corey- Chaykovsky, provide oxiranes, cyclopropane or aziridine, respectively. In this report, we try to introduce this important name reaction and highlight a comprehensive overview on the applications of this useful reaction in synthetic organic chemistry and total synthesis of natural products.
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Cite this article as:
M. Heravi Majid, Asadi Shima, Nazari Niousha and Malekzadeh Lashkariani Boshra, Developments of Corey-Chaykovsky in Organic Reactions and Total Synthesis of Natural Products, Current Organic Synthesis 2016; 13 (3) . https://dx.doi.org/10.2174/1570179412666150710182304
DOI https://dx.doi.org/10.2174/1570179412666150710182304 |
Print ISSN 1570-1794 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6271 |
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Organic synthesis is a fundamental discipline in chemistry, crucial for the creation of complex molecules with diverse applications in pharmaceuticals, materials science, and beyond. However, the process of designing efficient synthetic routes for target molecules remains challenging. Chemical graph theory, a branch of theoretical chemistry, offers powerful tools for understanding ...read more
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