A Survey of the Palladium-Catalyzed Hirao Reaction with Emphasis on Green Chemical Aspects

Title:A Survey of the Palladium-Catalyzed Hirao Reaction with Emphasis on Green Chemical Aspects

Volume: 2 Issue: 4

Author(s): Erzsébet Jablonkai and György Keglevich

Affiliation:

Keywords: Hirao reaction, P-C coupling, Pd-catalyst, phosphonates, phosphinates, phosphine oxides, P-ligand-free.

Abstract: The Pd-catalyzed P–C couplings of aryl, hetaryl and vinyl derivatives and species with a P(O)H function, typically dialkyl phosphites and secondary phosphine oxides giving rise to phosphonates and phosphine oxides are summarized with special emphasis on the green chemical variations. A great variety of reactions are discussed to demonstrate the different conditions and catalyst systems described. environmentally friendly protocols include the use of a phase transfer catalyst and the microwave technique. The best way is to perform the P–C coupling reactions under Pligand- free and solvent-free conditions.

Cite this article as:

Jablonkai Erzsébet and Keglevich György, A Survey of the Palladium-Catalyzed Hirao Reaction with Emphasis on Green Chemical Aspects, Current Green Chemistry 2015; 2 (4) . https://dx.doi.org/10.2174/2213346102999150630114117