Advances in Hyaluronic Acid-Based Drug Delivery Systems

Author(s): Yan Jiao, Xin Pang and Guangxi Zhai

Volume 17, Issue 6, 2016

Page: [720 - 730] Pages: 11

DOI: 10.2174/1389450116666150531155200

Price: $65

Abstract

Hyaluronic acid (HA) is a relatively new polymer for the construction of drug delivery systems. CD44 and the receptor for HA-mediated motility play a key role in vivo for the receptormediated endocytosis of HA. Cellular uptake and the efficiency of tumor-targeted drug delivery are supposed to increase through utilizing HA as drug carriers. Currently, HA has provided a promising platform to physically encapsulate or chemically conjugate with various drugs. In this review, we presented the most latest advances in HA-based drug delivery systems and some forward-looking ideas are discussed.

Keywords: CD44, chemical modification, conjugates, derivatives, hyaluronic acid, nanocarriers.

Graphical Abstract

Rights & Permissions Print Cite
© 2024 Bentham Science Publishers | Privacy Policy