Abstract
This review with 800 references illustrates applications of Suzuki-Miyaura (S.-M.) reactions in the total syntheses of 147 natural products that were made in the period 2010–2013. The review has been organized on the basis of the seven classes of phosphane-based Pd catalysts that have been used in the reported total syntheses. Emphasis has been given to describe and discuss the experimental conditions of the Pd-catalyzed (S.-M.) cross-coupling reactions also outlining the methods used to prepare the reactants. A focus has also been set on the biological and pharmacological properties of the reported natural products as well as on the most significant steps of the reported total syntheses.
Keywords: Carbon–carbon bond forming reactions, chemoselectivity, siteselectivity, stereoselectivity, transition metal catalyst.
Current Organic Chemistry
Title:Recent Applications of Phosphane-based Palladium Catalysts in Suzuki-Miyaura Reactions Involved in Total Syntheses of Natural Products
Volume: 19 Issue: 14
Author(s): Renzo Rossi, Fabio Bellina, Marco Lessi, Chiara Manzini, Giulia Marianetti and Luca A. Perego
Affiliation:
Keywords: Carbon–carbon bond forming reactions, chemoselectivity, siteselectivity, stereoselectivity, transition metal catalyst.
Abstract: This review with 800 references illustrates applications of Suzuki-Miyaura (S.-M.) reactions in the total syntheses of 147 natural products that were made in the period 2010–2013. The review has been organized on the basis of the seven classes of phosphane-based Pd catalysts that have been used in the reported total syntheses. Emphasis has been given to describe and discuss the experimental conditions of the Pd-catalyzed (S.-M.) cross-coupling reactions also outlining the methods used to prepare the reactants. A focus has also been set on the biological and pharmacological properties of the reported natural products as well as on the most significant steps of the reported total syntheses.
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Cite this article as:
Rossi Renzo, Bellina Fabio, Lessi Marco, Manzini Chiara, Marianetti Giulia and A. Perego Luca, Recent Applications of Phosphane-based Palladium Catalysts in Suzuki-Miyaura Reactions Involved in Total Syntheses of Natural Products, Current Organic Chemistry 2015; 19 (14) . https://dx.doi.org/10.2174/1385272819666150506230050
DOI https://dx.doi.org/10.2174/1385272819666150506230050 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
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