Abstract
Living systems have evolved a variety of complex nanostructures to control biomolecular interactions and biochemical reactions that are vital to the metabolism and reproduction. During the past few decades, single-molecule detection and imaging have been widely applied to interpreting biological processes in detail, which are able to observe the chemical reactions and kinetic behaviors of individual molecules. The rapid development of structural DNA nanotechnology has provided adaptable platforms to facilitate single-molecule detection and super-resolution imaging of individual biological components, as well as manipulating artificial nanosystems with molecular precision. In this review, we summarize recent exciting progress in using DNA nanostructures to sense and manipulate biomolecular interactions at the single-molecule level.
Keywords: AFM label-free detection, DNA nanostructures, nanorobots, single-molecule detection, super-resolution fluorescence imaging.
Graphical Abstract
Call for Papers in Thematic Issues
Role of nanomaterials in fabrication of coatings, Machining and Joining
The application of nanoscience has brought about a revolution in the field of mechanical engineering by providing novel materials, boosting manufacturing processes, and generating cutting-edge products. The purpose of this special issue is to investigate the enormous impact that nanoscience has had on mechanical engineering, with a particular emphasis on ...read more
Advanced Inorganic Nanocomposites and Their Emerging Applications
This special issue collection will highlight developments on the recent trends about the synthesis of metal oxides, nanoclusters, biomaterials, 2D nanomaterials, nanocrystals, nanocomposites, etc. and their applications in electrochemical systems, tissue regeneration, energy storage and harvesting, sensors, etc. The novelty of the methods in the chemical synthesis and their characterizations, ...read more
Applicability of Nanotechnology for Performance Enhancement of Clean Energy Technologies
Population growth, industrialization, and improvement in living quality would lead to further increase in energy demand in near future. Regarding the disadvantages of fossil fuels such as fluctuations in their price, high emissions of greenhouse gases and restriction of their sources, it is crucial to use and exploit alternative energy ...read more
Graphene and 2D Materials for Energy Storage and Conversion
This thematic issue will discuss the recent advances in graphene-based nanomaterials for different energy technologies. Graphene possesses a high surface area, and stable structure and exhibits many interesting electronic, optical, and mechanical properties due to its 2D crystal structure. Graphene is of both fundamental interest and suitable for a wide ...read more
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