Abstract
Predictable and complete periodontal regeneration following periodontitis has been the ultimate goal of periodontal treatment. It has been recognized that Hertwig’s epithelial root sheath (HERS) cells play a crucial role in cementogenesis and root formation. As the descendants of HERS and unique odontogenic epithelium in the adult periodontium, epithelial cell rests of Malassez (ERM) have long been considered as quiescent epithelial remnants devoid of structure and function. Here we will present an overview of our present understanding and putative functions of the ERM in the regeneration of periodontal tissues.
Keywords: Hertwig's epithelial root sheath, epithelial cell rests Malassez, periodontium development, periodontal regeneration, cementogenesis, stem cells.
Current Stem Cell Research & Therapy
Title:Role of the Epithelial Cell Rests of Malassez in Periodontal Homeostasis and Regeneration - A Review
Volume: 10 Issue: 5
Author(s): Zhenhua Yang, Yanjiao Li, Xiaojie Ma, Lin Shen, Zhihe Zhao and Fang Jin
Affiliation:
Keywords: Hertwig's epithelial root sheath, epithelial cell rests Malassez, periodontium development, periodontal regeneration, cementogenesis, stem cells.
Abstract: Predictable and complete periodontal regeneration following periodontitis has been the ultimate goal of periodontal treatment. It has been recognized that Hertwig’s epithelial root sheath (HERS) cells play a crucial role in cementogenesis and root formation. As the descendants of HERS and unique odontogenic epithelium in the adult periodontium, epithelial cell rests of Malassez (ERM) have long been considered as quiescent epithelial remnants devoid of structure and function. Here we will present an overview of our present understanding and putative functions of the ERM in the regeneration of periodontal tissues.
Export Options
About this article
Cite this article as:
Yang Zhenhua, Li Yanjiao, Ma Xiaojie, Shen Lin, Zhao Zhihe and Jin Fang, Role of the Epithelial Cell Rests of Malassez in Periodontal Homeostasis and Regeneration - A Review, Current Stem Cell Research & Therapy 2015; 10 (5) . https://dx.doi.org/10.2174/1574888X10666150312100957
DOI https://dx.doi.org/10.2174/1574888X10666150312100957 |
Print ISSN 1574-888X |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3946 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Antagonism by Bioactive Polyphenols Against Inflammation: A Systematic View
Inflammation & Allergy - Drug Targets (Discontinued) Beyond Hemostasis: The Role of Platelets in Inflammation, Malignancy and Infection
Cardiovascular & Hematological Disorders-Drug Targets Intra- and Interdomain Flexibility in Matrix Metalloproteinases: Functional Aspects and Drug Design
Current Pharmaceutical Design Editorial (Thematic Issue: Current Updates on Association Between Alzheimer’s Disease and Type 2 Diabetes Mellitus - Volume II)
CNS & Neurological Disorders - Drug Targets Extracorporeal Shock Wave Therapy in Inflammatory Diseases: Molecular Mechanism that Triggers Anti-Inflammatory Action
Current Medicinal Chemistry Redox Status in Periodontal and Systemic Inflammatory Conditions Including Associated Neoplasias: Antioxidants as Adjunctive Therapy?
Infectious Disorders - Drug Targets Wound Dressing Based Collagen Biomaterials Containing Usnic Acid as Quorum Sensing Inhibitor Agent: Synthesis, Characterization and Bioevaluation
Current Organic Chemistry A Review of Natural Products with Anti-Biofilm Activity
Current Organic Chemistry Phosphonate Emerging Zinc Binding Group in Matrix Metalloproteinase Inhibitors
Current Drug Targets Recent Biomedical Applications on Stem Cell Therapy: A Brief Overview
Current Stem Cell Research & Therapy Susceptibility Risk Alleles of -238G/A, -308G/A and -1031T/C Promoter Polymorphisms of TNF-α Gene to Uterine Leiomyomas
Recent Advances in DNA & Gene Sequences (Discontinued) Editorial (Thematic Issue: Modern and Alternative Matters in Oral Health Maintenance)
Mini-Reviews in Medicinal Chemistry The Rationale of Targeting Neutrophils with Dapsone during Glioblastoma Treatment
Anti-Cancer Agents in Medicinal Chemistry Periodontitis, Endothelial Dysfunction and Atherosclerosis
Vascular Disease Prevention (Discontinued) The Use of Intravenous Aminobisphosphonates for the Treatment of Pagets Disease of Bone
Mini-Reviews in Medicinal Chemistry Effect of Fibrin-binding Synthetic Oligopeptide on the Healing of Full-thickness Skin Wounds in Streptozotocin-induced Diabetic Rats
Current Pharmaceutical Design Influence of Antiretroviral Therapy and Periodontal Disease on Human Salivary Beta-Defensin 2 in Patients Infected with HIV
Current HIV Research Recent Developments in Bioactive Ceramic/Glass: Preparation and Application in Tissue Engineering and Drug Delivery
Recent Patents on Materials Science Riboswitches as Potential Targets for the Development of Anti-Biofilm Drugs
Current Topics in Medicinal Chemistry Emerging Molecular Targets for Treatment of Erectile Dysfunction: Vascular and Regenerative Therapies on the Horizon
Current Drug Targets