Abstract
Predictable and complete periodontal regeneration following periodontitis has been the ultimate goal of periodontal treatment. It has been recognized that Hertwig’s epithelial root sheath (HERS) cells play a crucial role in cementogenesis and root formation. As the descendants of HERS and unique odontogenic epithelium in the adult periodontium, epithelial cell rests of Malassez (ERM) have long been considered as quiescent epithelial remnants devoid of structure and function. Here we will present an overview of our present understanding and putative functions of the ERM in the regeneration of periodontal tissues.
Keywords: Hertwig's epithelial root sheath, epithelial cell rests Malassez, periodontium development, periodontal regeneration, cementogenesis, stem cells.
Current Stem Cell Research & Therapy
Title:Role of the Epithelial Cell Rests of Malassez in Periodontal Homeostasis and Regeneration - A Review
Volume: 10 Issue: 5
Author(s): Zhenhua Yang, Yanjiao Li, Xiaojie Ma, Lin Shen, Zhihe Zhao and Fang Jin
Affiliation:
Keywords: Hertwig's epithelial root sheath, epithelial cell rests Malassez, periodontium development, periodontal regeneration, cementogenesis, stem cells.
Abstract: Predictable and complete periodontal regeneration following periodontitis has been the ultimate goal of periodontal treatment. It has been recognized that Hertwig’s epithelial root sheath (HERS) cells play a crucial role in cementogenesis and root formation. As the descendants of HERS and unique odontogenic epithelium in the adult periodontium, epithelial cell rests of Malassez (ERM) have long been considered as quiescent epithelial remnants devoid of structure and function. Here we will present an overview of our present understanding and putative functions of the ERM in the regeneration of periodontal tissues.
Export Options
About this article
Cite this article as:
Yang Zhenhua, Li Yanjiao, Ma Xiaojie, Shen Lin, Zhao Zhihe and Jin Fang, Role of the Epithelial Cell Rests of Malassez in Periodontal Homeostasis and Regeneration - A Review, Current Stem Cell Research & Therapy 2015; 10 (5) . https://dx.doi.org/10.2174/1574888X10666150312100957
DOI https://dx.doi.org/10.2174/1574888X10666150312100957 |
Print ISSN 1574-888X |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3946 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
MicroRNA-203: Tumor Suppression and Beyond
MicroRNA Triphala in Prevention of Dental Caries and as an Antimicrobial in Oral Cavity- A Review
Infectious Disorders - Drug Targets The Impact of the Activated Stroma on Pancreatic Ductal Adenocarcinoma Biology and Therapy Resistance
Current Molecular Medicine Effect of HAART on Salivary Composition and Oxidative Profile in HIVInfected Patients
Current HIV Research Minocycline: Neuroprotective Mechanisms in Parkinsons Disease
Current Pharmaceutical Design The Origin and Identification of Mesenchymal Stem Cells in Teeth: from Odontogenic to Non-odontogenic
Current Stem Cell Research & Therapy Endotoxin, TLR4 Signaling and Vascular Inflammation: Potential Therapeutic Targets in Cardiovascular Disease
Current Pharmaceutical Design Periodontitis and Atherosclerosis, a Causal Relationship?
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry Oral Hygiene and Ventilator-Associated Pneumonia
Current Respiratory Medicine Reviews Applications of Mesoporous Materials as Excipients for Innovative Drug Delivery and Formulation
Current Pharmaceutical Design The Role of Parthenolide in Intracellular Signalling Processes: Review of Current Knowledge
Current Signal Transduction Therapy Meet Our Editorial Board Member:
Current Tissue Engineering (Discontinued) Redox Processes in Neurodegenerative Disease Involving Reactive Oxygen Species
Current Neuropharmacology Reactive Oxygen Species in Myocardial Reperfusion Injury: From Physiopathology to Therapeutic Approaches
Current Pharmaceutical Biotechnology Antimicrobial Efficacy of Extemporaneously Prepared Herbal Mouthwashes
Recent Patents on Drug Delivery & Formulation Matrix Metalloproteinases as Valid Clinical Target
Current Pharmaceutical Design Lipid Matrix Systems with Emphasis on Lipid Microspheres: Potent Carriers for Transcutaneous Delivery of Bioactives
Current Drug Delivery Risk Factors, Mechanisms and Treatments of Thromboangiitis Obliterans: An Overview of Recent Research
Current Medicinal Chemistry Biomarkers of Regenerative Responses to Phenytoin in Periosteal Fibroblasts and Modulation by Histamine; Relevance to Inflammatory Repair
Recent Patents on Biomarkers Targets for Steroid Hormone Mediated Actions of Periodontal Pathogens, Cytokines and Therapeutic Agents Some Implications on Tissue Turnover in the Periodontium
Current Drug Targets