Abstract
Fused heterocycles constitute the largest diversity of heterocyclic compounds of chemical and biomedical significance. They widely exist in numerous natural products. They are also among the most frequently encountered scaffolds in numerous drugs and pharmaceutically relevant substances. This review highlights some remarkable achievements made in the synthesis and chemistry of pyridotriazolopyrimidines that have appeared in more than the last three decades. The latter heterocyclic ring systems have more than twenty five structures. Moreover, the biological importance of such ring systems is discussed.
Keywords: Biological activity, pyridotriazolopyrimidines, reactions, synthesis.
Graphical Abstract
Call for Papers in Thematic Issues
Exploring the Role of Chemical Graph Theory in Advancing Current Organic Synthesis
Organic synthesis is a fundamental discipline in chemistry, crucial for the creation of complex molecules with diverse applications in pharmaceuticals, materials science, and beyond. However, the process of designing efficient synthetic routes for target molecules remains challenging. Chemical graph theory, a branch of theoretical chemistry, offers powerful tools for understanding ...read more
Photoswitches for Molecular Recognition
This Special Issue would cover the hot topics on synthesis and chemical and photophysical characterization of new photoswitchable derivatives and their applications on molecular recognition of metabolites and biological active compounds, both in physiological medium and in living cells. Photoswitches are compounds that can change their conformation or properties in ...read more
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