N-Methyl-2-Chloropyridinium Iodide/NaNO₂/Wet SiO₂: Neutral Reagent System for the Nitration of Activated Aromatic Compounds under Very Mild Conditions

Title:N-Methyl-2-Chloropyridinium Iodide/NaNO₂/Wet SiO₂: Neutral Reagent System for the Nitration of Activated Aromatic Compounds under Very Mild Conditions

Volume: 12 Issue: 2

Author(s): Roya Azadi and Zahra Nazari-Far

Affiliation:

Keywords: Aromatic compounds, mukaiyama reagent, N-methyl-2-chloropyridinium iodide, nitration, sodium nitrite.

Abstract: Mononitration of activated aromatic compounds using N-methyl-2-chloro-pyridinium iodide (Mukaiyama reagent)/ NaNO₂/wet SiO₂ reagent system under neutral, very mild and environmentally safer reaction condition has been developed. Various structurally diverse aromatic rings are subjected in this condition and the corresponding nitro-aromatic compounds are prepared in moderately high yields.

Cite this article as:

Azadi Roya and Nazari-Far Zahra, N-Methyl-2-Chloropyridinium Iodide/NaNO₂/Wet SiO₂: Neutral Reagent System for the Nitration of Activated Aromatic Compounds under Very Mild Conditions, Letters in Organic Chemistry 2015; 12 (2) . https://dx.doi.org/10.2174/157017861202150213105836