Abstract
Orthopedic disorders and trauma usually result in bone loss. Bone grafts are widely used to replace this tissue. Bone grafts excluding autografts unfortunately have disadvantages like evoking immune response, contamination and rejection. Autografts are of limited sources and optimum biomaterials that can replace bone have been searched for several decades. Bioceramics, which have the similar inorganic structure of natural bone, are widely used to regenerate bone or coat metallic implants. As people continuously look for a higher life quality, there are developments in technology almost everyday to meet their expectations. Nanotechnology is one of such technologies and it attracts everyone’s attention in biomaterial science. Nano scale biomaterials have many advantages like larger surface area and higher biocompatibility and these properties make them more preferable than micro scale. Also, stem cells are used for bone regeneration besides nano-bioceramics due to their differentiation characteristics. This review covers current research on nano-bioceramics and mesenchymal stem cells and their role in bone regeneration.
Keywords: Bioceramics, bone, mesenchymal stem cells, nano scale, regeneration, tissue engineering.
Current Stem Cell Research & Therapy
Title:Mesenchymal Stem Cells and Nano-Bioceramics for Bone Regeneration
Volume: 11 Issue: 6
Author(s): Berna Kankilic, Sevil Köse, Petek Korkusuz, Muharrem Timuçin and Feza Korkusuz
Affiliation:
Keywords: Bioceramics, bone, mesenchymal stem cells, nano scale, regeneration, tissue engineering.
Abstract: Orthopedic disorders and trauma usually result in bone loss. Bone grafts are widely used to replace this tissue. Bone grafts excluding autografts unfortunately have disadvantages like evoking immune response, contamination and rejection. Autografts are of limited sources and optimum biomaterials that can replace bone have been searched for several decades. Bioceramics, which have the similar inorganic structure of natural bone, are widely used to regenerate bone or coat metallic implants. As people continuously look for a higher life quality, there are developments in technology almost everyday to meet their expectations. Nanotechnology is one of such technologies and it attracts everyone’s attention in biomaterial science. Nano scale biomaterials have many advantages like larger surface area and higher biocompatibility and these properties make them more preferable than micro scale. Also, stem cells are used for bone regeneration besides nano-bioceramics due to their differentiation characteristics. This review covers current research on nano-bioceramics and mesenchymal stem cells and their role in bone regeneration.
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Cite this article as:
Kankilic Berna, Köse Sevil, Korkusuz Petek, Timuçin Muharrem and Korkusuz Feza, Mesenchymal Stem Cells and Nano-Bioceramics for Bone Regeneration, Current Stem Cell Research & Therapy 2016; 11 (6) . https://dx.doi.org/10.2174/1574888X10666150202150518
DOI https://dx.doi.org/10.2174/1574888X10666150202150518 |
Print ISSN 1574-888X |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3946 |
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