Abstract
Polyphenols are an extensive group of substances present in plants. Animals and humans achieve them through the diet. Polyphenols have been related to several processes, such as oxidative stress and signaling pathways modulating gene expression that promote an anti-inflammatory environment. Moreover, polyphenols also have a possible role in the protection of several diseases, including major depression. Depression is an important public-health problem with a multifactorial etiology and lots of pathways that can be altered in affected subjects. Moreover, this disease can be affected by exercise, sleep and diet. There are animal works studying polyphenols and depression, but human studies are scarce. This review summarizes recent evidences in relation to the effects of polyphenols as antidepressant agents in the depression.
Keywords: Antidepressant, depression, inflammation, oxidative stress, public-health, polyphenol.
Current Pharmaceutical Biotechnology
Title:Polyphenols and Depression: from Chemistry to Medicine
Volume: 16 Issue: 3
Author(s): Antoni Sureda and Silvia Tejada
Affiliation:
Keywords: Antidepressant, depression, inflammation, oxidative stress, public-health, polyphenol.
Abstract: Polyphenols are an extensive group of substances present in plants. Animals and humans achieve them through the diet. Polyphenols have been related to several processes, such as oxidative stress and signaling pathways modulating gene expression that promote an anti-inflammatory environment. Moreover, polyphenols also have a possible role in the protection of several diseases, including major depression. Depression is an important public-health problem with a multifactorial etiology and lots of pathways that can be altered in affected subjects. Moreover, this disease can be affected by exercise, sleep and diet. There are animal works studying polyphenols and depression, but human studies are scarce. This review summarizes recent evidences in relation to the effects of polyphenols as antidepressant agents in the depression.
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Cite this article as:
Sureda Antoni and Tejada Silvia, Polyphenols and Depression: from Chemistry to Medicine, Current Pharmaceutical Biotechnology 2015; 16 (3) . https://dx.doi.org/10.2174/1389201016666150118133313
DOI https://dx.doi.org/10.2174/1389201016666150118133313 |
Print ISSN 1389-2010 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4316 |
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