Abstract
Polyphenols are an extensive group of substances present in plants. Animals and humans achieve them through the diet. Polyphenols have been related to several processes, such as oxidative stress and signaling pathways modulating gene expression that promote an anti-inflammatory environment. Moreover, polyphenols also have a possible role in the protection of several diseases, including major depression. Depression is an important public-health problem with a multifactorial etiology and lots of pathways that can be altered in affected subjects. Moreover, this disease can be affected by exercise, sleep and diet. There are animal works studying polyphenols and depression, but human studies are scarce. This review summarizes recent evidences in relation to the effects of polyphenols as antidepressant agents in the depression.
Keywords: Antidepressant, depression, inflammation, oxidative stress, public-health, polyphenol.
Current Pharmaceutical Biotechnology
Title:Polyphenols and Depression: from Chemistry to Medicine
Volume: 16 Issue: 3
Author(s): Antoni Sureda and Silvia Tejada
Affiliation:
Keywords: Antidepressant, depression, inflammation, oxidative stress, public-health, polyphenol.
Abstract: Polyphenols are an extensive group of substances present in plants. Animals and humans achieve them through the diet. Polyphenols have been related to several processes, such as oxidative stress and signaling pathways modulating gene expression that promote an anti-inflammatory environment. Moreover, polyphenols also have a possible role in the protection of several diseases, including major depression. Depression is an important public-health problem with a multifactorial etiology and lots of pathways that can be altered in affected subjects. Moreover, this disease can be affected by exercise, sleep and diet. There are animal works studying polyphenols and depression, but human studies are scarce. This review summarizes recent evidences in relation to the effects of polyphenols as antidepressant agents in the depression.
Export Options
About this article
Cite this article as:
Sureda Antoni and Tejada Silvia, Polyphenols and Depression: from Chemistry to Medicine, Current Pharmaceutical Biotechnology 2015; 16 (3) . https://dx.doi.org/10.2174/1389201016666150118133313
DOI https://dx.doi.org/10.2174/1389201016666150118133313 |
Print ISSN 1389-2010 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4316 |
Call for Papers in Thematic Issues
Artificial Intelligence in Bioinformatics
Bioinformatics is an interdisciplinary field that analyzes and explores biological data. This field combines biology and information system. Artificial Intelligence (AI) has attracted great attention as it tries to replicate human intelligence. It has become common technology for analyzing and solving complex data and problems and encompasses sub-fields of machine ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
WT1 Peptide Vaccine as a Paradigm for “Cancer Antigen-Derived Peptide”-Based Immunotherapy for Malignancies: Successful Induction of Anti-Cancer Effect by Vaccination with a Single Kind of WT1 Peptide
Anti-Cancer Agents in Medicinal Chemistry Economics of Pharmacogenomics: Rethinking Beyond QALYs?
Current Pharmacogenomics and Personalized Medicine Safety of Multi-Targeted Kinase Inhibitors as Monotherapy Treatment of Cancer: A Systematic Review of the Literature
Current Drug Safety Peripheral Benzodiazepine Receptor Ligands and their Anti-Inflammatory Effects
Current Medicinal Chemistry - Anti-Inflammatory & Anti-Allergy Agents What Western Pharmacists Need to Know About Traditional Chinese Medicine; A Canadian Perspective
Current Traditional Medicine Applications of Nanosystems to Anticancer Drug Therapy (Part I. Nanogels, Nanospheres, Nanocapsules)
Recent Patents on Anti-Cancer Drug Discovery Immune Dysfunction in Chronic Lymphocytic Leukemia: The Role for Immunotherapy
Current Pharmaceutical Design Phosphatidylinositol 3-kinase Signaling as a Therapeutic Target for Cervical Cancer
Current Cancer Drug Targets Akt in Prostate Cancer: Possible Role in Androgen-Independence
Current Drug Metabolism The Involvement of Post-Translational Modifications in Alzheimer's Disease
Current Alzheimer Research Critical Roles of EGFR Family Members in Breast Cancer and Breast Cancer Stem Cells: Targets for Therapy
Current Pharmaceutical Design Redox-active and Redox-silent Compounds: Synergistic Therapeutics in Cancer
Current Medicinal Chemistry SHP-2 Regulates Growth Factor Dependent Vascular Signalling and Function
Mini-Reviews in Medicinal Chemistry Chemotherapy and Target Therapy in the Management of Adult High- Grade Gliomas
Current Cancer Drug Targets The Role of Integrins in Glioma Biology and Anti-Glioma Therapies
Current Pharmaceutical Design Synthesis, Selective Cancer Cytotoxicity and Mechanistic Studies of Novel Analogs of Lantadenes
Anti-Cancer Agents in Medicinal Chemistry Lumiflavin Enhances the Effects of Ionising Radiation on Ovarian Cancer Stem-Like Cells by Inhibiting Autophagy
Anti-Cancer Agents in Medicinal Chemistry In vivo behavior and Safety of Lapatinib-Incorporated Lipid Nanoparticles
Current Pharmaceutical Biotechnology Targeting Stem Cells-Clinical Implications for Cancer Therapy
Current Stem Cell Research & Therapy Current Update on Eosinophilic Lung Diseases and Anti-IL-5 Treatment
Recent Patents on Anti-Infective Drug Discovery