Abstract
The mortality rate among patients suffering acute respiratory distress syndrome (ARDS) remains high despite implementation at clinical centers of the lung protective ventilatory strategies recommended by the International Guidelines for Management of Severe Sepsis and Septic Shock, 2012. This suggests that such strategies are still sub-optimal for some ARDS patients. For these patients, tailored use of ventilator settings should be considered, including: further reduction of tidal volumes, administration of neuromuscular blocking agents if the patient’s spontaneous breathing is incompatible with mechanical ventilation, and adjusting positive end-expiratory pressure (PEEP) settings based on transpulmonary pressure levels.
Keywords: ARDS, transpulmonary pressure, lung protective strategy, strain.
Cardiovascular & Hematological Disorders-Drug Targets
Title:Mechanical Ventilation for ARDS Patients – For a Better Understanding of the 2012 Surviving Sepsis Campaign Guidelines
Volume: 15 Issue: 1
Author(s): Muneyuki Takeuchi and Kazuya Tachibana
Affiliation:
Keywords: ARDS, transpulmonary pressure, lung protective strategy, strain.
Abstract: The mortality rate among patients suffering acute respiratory distress syndrome (ARDS) remains high despite implementation at clinical centers of the lung protective ventilatory strategies recommended by the International Guidelines for Management of Severe Sepsis and Septic Shock, 2012. This suggests that such strategies are still sub-optimal for some ARDS patients. For these patients, tailored use of ventilator settings should be considered, including: further reduction of tidal volumes, administration of neuromuscular blocking agents if the patient’s spontaneous breathing is incompatible with mechanical ventilation, and adjusting positive end-expiratory pressure (PEEP) settings based on transpulmonary pressure levels.
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Cite this article as:
Takeuchi Muneyuki and Tachibana Kazuya, Mechanical Ventilation for ARDS Patients – For a Better Understanding of the 2012 Surviving Sepsis Campaign Guidelines , Cardiovascular & Hematological Disorders-Drug Targets 2015; 15 (1) . https://dx.doi.org/10.2174/1871529X15666150108113853
DOI https://dx.doi.org/10.2174/1871529X15666150108113853 |
Print ISSN 1871-529X |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-4063 |
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