Abstract
Nanohydrogel combines the advantages of hydrogel and nano particulate systems. Similar to the hydrogel and macrogel, nanohydrogel can protect the drug and control drug release by stimuli responsive conformation or biodegradable bond into the polymer networks. Nanohydrogel has drawn huge interest due to their potential applications, such as carrier in target-specific controlled drug delivery, absorbents, chemical/biological sensors, and bio-mimetic materials. Similar to the nanoparticles, stimuli responsive nanohydrogel can easily be delivered in the liquid form for parenteral drug delivery application. This review highlights the methods to prepare nanohydrogel based on natural and synthetic polymers for diverse applications in drug delivery. It also encompasses the drug loading and drug release mechanism of the nanohydrogel formulation and patents related to the composition and chemical methods for preparation of nanohydrogel formulation with current status in clinical trials.
Keywords: Biocompatibility, cross-linked, drug delivery, nanoparticle, nanocomposite, thermoresponsive.
Recent Patents on Nanotechnology
Title:Application of Nanohydrogels in Drug Delivery Systems: Recent Patents Review
Volume: 9 Issue: 1
Author(s): Chintan Dalwadi and Gayatri Patel
Affiliation:
Keywords: Biocompatibility, cross-linked, drug delivery, nanoparticle, nanocomposite, thermoresponsive.
Abstract: Nanohydrogel combines the advantages of hydrogel and nano particulate systems. Similar to the hydrogel and macrogel, nanohydrogel can protect the drug and control drug release by stimuli responsive conformation or biodegradable bond into the polymer networks. Nanohydrogel has drawn huge interest due to their potential applications, such as carrier in target-specific controlled drug delivery, absorbents, chemical/biological sensors, and bio-mimetic materials. Similar to the nanoparticles, stimuli responsive nanohydrogel can easily be delivered in the liquid form for parenteral drug delivery application. This review highlights the methods to prepare nanohydrogel based on natural and synthetic polymers for diverse applications in drug delivery. It also encompasses the drug loading and drug release mechanism of the nanohydrogel formulation and patents related to the composition and chemical methods for preparation of nanohydrogel formulation with current status in clinical trials.
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Cite this article as:
Dalwadi Chintan and Patel Gayatri, Application of Nanohydrogels in Drug Delivery Systems: Recent Patents Review, Recent Patents on Nanotechnology 2015; 9 (1) . https://dx.doi.org/10.2174/1872210509666150101151521
DOI https://dx.doi.org/10.2174/1872210509666150101151521 |
Print ISSN 1872-2105 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-4020 |
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