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Current Bioactive Compounds

Editor-in-Chief

ISSN (Print): 1573-4072
ISSN (Online): 1875-6646

Antitumor Metabolites of Fungi

Author(s): Rosario Nicoletti and Antonio Fiorentino

Volume 10, Issue 4, 2014

Page: [207 - 244] Pages: 38

DOI: 10.2174/1573407211666141224204809

Price: $65

Abstract

The exploitation of the antitumor properties of fungal secondary metabolites is one of the fundamental objectives pursued by a multiplicity of research groups and laboratories working on the characterization of natural products worldwide. The availability of a synthetic framework on such a vast interdisciplinary topic can enhance the current knowledge by supporting novel findings, and stimulating further insights. This paper offers an overview of the state-of-the-art concerning this category of compounds and their occurrence, selection, structural diversity and mechanisms of action on tumor cells.

Keywords: Antitumor drugs, biological activity, fungi, natural products, secondary metabolites.


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