Abstract
Non-alcoholic fatty liver disease (NAFLD) is extremely prevalent in the Western world. Non-invasive diagnostic methods should be able to reflect the presence and severity of liver fatty changes and the presence and severity of hepatic inflammation and fibrosis (features of non-alcoholic steato-hepatitis), since these are related to the risk of progression and clinical complications.
This article will: a) review the rational basis for the use of ultrasound and transient elastography in patients with NAFLD; b) summarize available data regarding the diagnostic performance of these two widely used non-invasive imaging methods in patients with NAFLD; and c) give an overview of newer sonographic applications that might be used in clinical practice in the near future in this field.
Keywords: ARFI, cirrhosis, controlled attenuation parameter, liver fibrosis, NASH, sonography.
Reviews on Recent Clinical Trials
Title:Non-Invasive Assessment of Non-Alcoholic Fatty Liver Disease: Ultrasound and Transient Elastography
Volume: 9 Issue: 3
Author(s): Annalisa Berzigotti
Affiliation:
Keywords: ARFI, cirrhosis, controlled attenuation parameter, liver fibrosis, NASH, sonography.
Abstract: Non-alcoholic fatty liver disease (NAFLD) is extremely prevalent in the Western world. Non-invasive diagnostic methods should be able to reflect the presence and severity of liver fatty changes and the presence and severity of hepatic inflammation and fibrosis (features of non-alcoholic steato-hepatitis), since these are related to the risk of progression and clinical complications.
This article will: a) review the rational basis for the use of ultrasound and transient elastography in patients with NAFLD; b) summarize available data regarding the diagnostic performance of these two widely used non-invasive imaging methods in patients with NAFLD; and c) give an overview of newer sonographic applications that might be used in clinical practice in the near future in this field.
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Cite this article as:
Berzigotti Annalisa, Non-Invasive Assessment of Non-Alcoholic Fatty Liver Disease: Ultrasound and Transient Elastography, Reviews on Recent Clinical Trials 2014; 9 (3) . https://dx.doi.org/10.2174/1574887109666141216101630
DOI https://dx.doi.org/10.2174/1574887109666141216101630 |
Print ISSN 1574-8871 |
Publisher Name Bentham Science Publisher |
Online ISSN 1876-1038 |
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