Abstract
The objective of this paper is to review the evidence testing the possible benefit of vitamin D replacement on diabetes control and complications.
Type 2 diabetes mellitus (DM 2) has become a significant global health care problem and its reported incidence is increasing at an alarming rate. Despite the improvement in therapy and development of new drugs, treatment is still not optimal especially with the associated adverse effects of most of the available drugs. New efforts are shifted toward disease prevention and a search for safer drugs. New mounting evidence is associating low vitamin D to diabetes mellitus and as such many studies were conducted to test the effect of vitamin D replacement on incidence of diabetes, diabetes control as well as diabetes complications.
Although these studies present several limitations, vitamin D replacement seems to have beneficial effect on all aspects of diabetes: incidence, control and complications. Further longer term and more powered controlled trials are necessary to draw firmer conclusions on this beneficial role of vitamin D treatment on DM.
Keywords: 25 hydroxy vitamin D, type 2 diabetes mellitus, vitamin D replacement, 25 hydroxy vitamin D deficiency, diabetes control, diabetes complications.
Current Diabetes Reviews
Title:Vitamin D Replacement and Type 2 Diabetes Mellitus
Volume: 11 Issue: 1
Author(s): Claire. M. Issa, Mira S. Zantout and Sami T. Azar
Affiliation:
Keywords: 25 hydroxy vitamin D, type 2 diabetes mellitus, vitamin D replacement, 25 hydroxy vitamin D deficiency, diabetes control, diabetes complications.
Abstract: The objective of this paper is to review the evidence testing the possible benefit of vitamin D replacement on diabetes control and complications.
Type 2 diabetes mellitus (DM 2) has become a significant global health care problem and its reported incidence is increasing at an alarming rate. Despite the improvement in therapy and development of new drugs, treatment is still not optimal especially with the associated adverse effects of most of the available drugs. New efforts are shifted toward disease prevention and a search for safer drugs. New mounting evidence is associating low vitamin D to diabetes mellitus and as such many studies were conducted to test the effect of vitamin D replacement on incidence of diabetes, diabetes control as well as diabetes complications.
Although these studies present several limitations, vitamin D replacement seems to have beneficial effect on all aspects of diabetes: incidence, control and complications. Further longer term and more powered controlled trials are necessary to draw firmer conclusions on this beneficial role of vitamin D treatment on DM.
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Cite this article as:
M. Issa Claire., S. Zantout Mira and T. Azar Sami, Vitamin D Replacement and Type 2 Diabetes Mellitus, Current Diabetes Reviews 2015; 11 (1) . https://dx.doi.org/10.2174/1573399811666141210153503
DOI https://dx.doi.org/10.2174/1573399811666141210153503 |
Print ISSN 1573-3998 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6417 |
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