Abstract
Diabetes mellitus has been increasing rapidly worldwide, making it a huge health pressure on society in both the developed and developing countries. During the last thirty years, diabetes mellitus, a chronic metabolic disease characterized by hyperglycemia is proving itself to be fatal. Periodontitis was considered as one of the main, oral health problems encountered in patients with diabetes mellitus. There exists a direct relation between the risk of complications of diabetes and periodontitis over time. The present review gives an outline of the features that govern the interrelationship between zinc and diabetes mellitus with periodontal disease, including the physiologic mechanisms and clinical studies, and presents scientific evidences. The disturbance in the zinc micronutrient and increased oxidative stress in type 2 diabetes may bring about insulin resistance and the creation of diabetic complications. The progression of diabetes mellitus may bring about perturbation in micronutrient metabolism and status.
Keywords: Micronutrients, oxidative stress, periodontitis, tissue damage, type 2 diabetes mellitus, zinc.
Current Diabetes Reviews
Title:Zinc and Type 2 Diabetes Mellitus with Periodontitis- A Systematic Review
Volume: 10 Issue: 6
Author(s): D.S. Pushparani
Affiliation:
Keywords: Micronutrients, oxidative stress, periodontitis, tissue damage, type 2 diabetes mellitus, zinc.
Abstract: Diabetes mellitus has been increasing rapidly worldwide, making it a huge health pressure on society in both the developed and developing countries. During the last thirty years, diabetes mellitus, a chronic metabolic disease characterized by hyperglycemia is proving itself to be fatal. Periodontitis was considered as one of the main, oral health problems encountered in patients with diabetes mellitus. There exists a direct relation between the risk of complications of diabetes and periodontitis over time. The present review gives an outline of the features that govern the interrelationship between zinc and diabetes mellitus with periodontal disease, including the physiologic mechanisms and clinical studies, and presents scientific evidences. The disturbance in the zinc micronutrient and increased oxidative stress in type 2 diabetes may bring about insulin resistance and the creation of diabetic complications. The progression of diabetes mellitus may bring about perturbation in micronutrient metabolism and status.
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Cite this article as:
Pushparani D.S., Zinc and Type 2 Diabetes Mellitus with Periodontitis- A Systematic Review, Current Diabetes Reviews 2014; 10 (6) . https://dx.doi.org/10.2174/1573399810666141121161514
DOI https://dx.doi.org/10.2174/1573399810666141121161514 |
Print ISSN 1573-3998 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6417 |
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