Abstract
Microfluidics is a compelling technology that shows considerable promise in applications ranging from gene expression profiling to cell-based assays. Owing to its capacity to enable generation of single droplets and multiple droplet arrays with precisely controlled composition and a narrow size distribution, recently microfluidics has been exploited for delivery of genes. This article provides an overview of recent advances in microfluidic gene delivery, and speculates the prospects for further research. The objectives of this article are to illustrate the potential roles played by microfluidics in gene delivery research, and to shed new light on strategies to enhance the efficiency of gene therapy.
Keywords: Droplet, gene delivery, gene therapy, microfluidics, microfabrication.
Current Gene Therapy
Title:Microfluidic Methods for Non-Viral Gene Delivery
Volume: 15 Issue: 1
Author(s): Wing-Fu Lai
Affiliation:
Keywords: Droplet, gene delivery, gene therapy, microfluidics, microfabrication.
Abstract: Microfluidics is a compelling technology that shows considerable promise in applications ranging from gene expression profiling to cell-based assays. Owing to its capacity to enable generation of single droplets and multiple droplet arrays with precisely controlled composition and a narrow size distribution, recently microfluidics has been exploited for delivery of genes. This article provides an overview of recent advances in microfluidic gene delivery, and speculates the prospects for further research. The objectives of this article are to illustrate the potential roles played by microfluidics in gene delivery research, and to shed new light on strategies to enhance the efficiency of gene therapy.
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Cite this article as:
Lai Wing-Fu, Microfluidic Methods for Non-Viral Gene Delivery, Current Gene Therapy 2015; 15 (1) . https://dx.doi.org/10.2174/1566523214666141114213915
DOI https://dx.doi.org/10.2174/1566523214666141114213915 |
Print ISSN 1566-5232 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5631 |
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