Abstract
Aim: To conduct a systematic review which examined the effectiveness of footwear and other removable off-loading devices as interventions for the treatment of diabetic foot ulcers or the alteration of biomechanical factors associated with ulcer healing and to discuss the quality and interpret the findings of research to date.
Methods: The CINAHL, Medline and Cochrane Register of Controlled Trials databases were searched with seventeen articles identified for review.
Results: Majority of the identified studies were randomised control trials which compared the ulcer healing rates of different footwear and other removable off-loading device interventions. Three categories of interventions were identified; 1) removable cast walkers (RCWs), 2) half or heel relief shoes and 3) therapeutic shoes. Most studies compared at least one intervention to a total contact cast (TCC). Factors which influenced study findings such as TCC application method, compliance, activity levels, and the footwear worn on the contralateral limb are discussed with recommendations provided for future studies.
Conclusion: Due to the lack of randomised controlled studies conducted in this area it is not currently possible to make strong conclusions on the interventions effectiveness. However, it appears the currently available therapeutic shoes were the least effective intervention followed by half or heel relief shoes. RCWs were found to be the most effective of the removable devices.
Keywords: Biomechanics, diabetes, footwear, plantar pressure, pressure reduction, ulceration.
Current Diabetes Reviews
Title:The Effectiveness of Footwear and Other Removable Off-loading Devices in the Treatment of Diabetic Foot Ulcers: A Systematic Review
Volume: 10 Issue: 4
Author(s): Aoife Healy, Roozbeh Naemi and Nachiappan Chockalingam
Affiliation:
Keywords: Biomechanics, diabetes, footwear, plantar pressure, pressure reduction, ulceration.
Abstract: Aim: To conduct a systematic review which examined the effectiveness of footwear and other removable off-loading devices as interventions for the treatment of diabetic foot ulcers or the alteration of biomechanical factors associated with ulcer healing and to discuss the quality and interpret the findings of research to date.
Methods: The CINAHL, Medline and Cochrane Register of Controlled Trials databases were searched with seventeen articles identified for review.
Results: Majority of the identified studies were randomised control trials which compared the ulcer healing rates of different footwear and other removable off-loading device interventions. Three categories of interventions were identified; 1) removable cast walkers (RCWs), 2) half or heel relief shoes and 3) therapeutic shoes. Most studies compared at least one intervention to a total contact cast (TCC). Factors which influenced study findings such as TCC application method, compliance, activity levels, and the footwear worn on the contralateral limb are discussed with recommendations provided for future studies.
Conclusion: Due to the lack of randomised controlled studies conducted in this area it is not currently possible to make strong conclusions on the interventions effectiveness. However, it appears the currently available therapeutic shoes were the least effective intervention followed by half or heel relief shoes. RCWs were found to be the most effective of the removable devices.
Export Options
About this article
Cite this article as:
Healy Aoife, Naemi Roozbeh and Chockalingam Nachiappan, The Effectiveness of Footwear and Other Removable Off-loading Devices in the Treatment of Diabetic Foot Ulcers: A Systematic Review, Current Diabetes Reviews 2014; 10 (4) . https://dx.doi.org/10.2174/1573399810666140918121438
DOI https://dx.doi.org/10.2174/1573399810666140918121438 |
Print ISSN 1573-3998 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6417 |
Call for Papers in Thematic Issues
Advancing Diabetic Wound Healing: Mechanisms and Interventions
In recent years, diabetic wounds have become a global health concern with the increase in the incidence of diabetes. Diabetic wounds are a kind of chronic and refractory ulcer. It is generally due to the microcirculatory disturbances and the reduced levels of endogenous growth factors. Delayed cutaneous wound healing is ...read more
Oxidative and inflammatory responses in the development of secondary diabetic complications
Diabetes, along with its associated secondary complications, represents a significant global health challenge, contributing significantly to morbidity and mortality. Unhealthy lifestyle habits, reduced physical activity, environmental pollutants, and stress are pivotal factors in the onset of diabetes, particularly type-2 diabetes. Poorly managed hyperglycemia can lead to various complications, including neuropathy, ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Preparation of Chitosan/Alginate-ellagic Acid Sustained-release Microspheres and their Inhibition of Preadipocyte Adipogenic Differentiation
Current Pharmaceutical Biotechnology Effects of Pterostilbene on Diabetes, Liver Steatosis and Serum Lipids
Current Medicinal Chemistry Subject Index to Volume 2
Current Medicinal Chemistry - Cardiovascular & Hematological Agents Mechanisms of Protective Effects of SGLT2 Inhibitors in Cardiovascular Disease and Renal Dysfunction
Current Topics in Medicinal Chemistry Genetic Analysis of Aldose Reductase in Diabetic Complications
Current Medicinal Chemistry Connectivity and Patterns of Regional Cerebral Blood Flow, Cerebral Glucose Uptake, and Aβ-Amyloid Deposition in Alzheimer's Disease (Early and Late-Onset) Compared to Normal Ageing
Current Alzheimer Research An Analysis of Federal Circuit Discrimination: The Evolution of the Written Description Requirement Vis-a-Vis DNA and Biotechnological Inventions Concerns for Synthetic Biology
Recent Patents on DNA & Gene Sequences Growth Factor Delivery to Re-Engineer Periodontal Tissues
Current Pharmaceutical Biotechnology PEGylated Liposomal Vancomycin: A Glimmer of Hope for Improving Treatment Outcomes in MRSA Pneumonia
Recent Patents on Anti-Infective Drug Discovery Phyto-glycosides as Therapeutic Target in the Treatment of Diabetes
Mini-Reviews in Medicinal Chemistry Purine Ionotropic (P2X) Receptors
Current Pharmaceutical Design Modification of the In Vitro Release Profile of Cetrorelix by Complexation with Biophilic Partners
Current Drug Delivery Surreptitious TB Infections with Recently Identified DM People: A Cross- Sectional Study
Infectious Disorders - Drug Targets Ascorbic Acid: An Old Player with a Broad Impact on Body Physiology Including Oxidative Stress Suppression and Immunomodulation: A Review
Mini-Reviews in Medicinal Chemistry The Role of Alpha-lipoic Acid Supplementation in the Prevention of Diabetes Complications: A Comprehensive Review of Clinical Trials
Current Diabetes Reviews Acute Inflammation and Oxidative Stress Induced by Lipopolysaccharide and the Ameliorative Effect of Stingless Bee Honey
Combinatorial Chemistry & High Throughput Screening Gastrointestinal Immune System and Brain Dialogue Implicated in Neuroinflammatory and Neurodegenerative Diseases
Current Molecular Medicine The Role of (Modified) Lipoproteins in Vascular Function: A Duet Between Monocytes and the Endothelium
Current Medicinal Chemistry Development of New Antituberculous Drugs: Strategies for New Drug Targets and Drug Delivery
Drug Design Reviews - Online (Discontinued) Adipokine Visfatin’s Role in Pathogenesis of Diabesity and Related Metabolic Derangements
Current Molecular Medicine