Abstract
Aside from its actions on glycaemic control, insulin has been demonstrated to have a wide range of effects on the cardiovascular system. During the peri-operative period, the stress response to surgery leads to hyperglycaemia. There is continuing debate with regard to the level of glycaemic control and the potential benefits of insulin therapy in both diabetic and non-diabetic patients undergoing cardiac surgery. This review article sets out to discuss the evidence for glycaemic control, as well as the potential benefits of insulin therapy in the form of glucose-insulin-potassium therapy in cardiac surgery.
Keywords: Cardiac surgery, coronary artery bypass grafting, diabetes, glucose-insulin-potassium, insulin, metabolism.
Current Diabetes Reviews
Title:Insulin Therapy in Cardiac Surgery
Volume: 10 Issue: 4
Author(s): Ashvini Menon and A. M. Ranasinghe
Affiliation:
Keywords: Cardiac surgery, coronary artery bypass grafting, diabetes, glucose-insulin-potassium, insulin, metabolism.
Abstract: Aside from its actions on glycaemic control, insulin has been demonstrated to have a wide range of effects on the cardiovascular system. During the peri-operative period, the stress response to surgery leads to hyperglycaemia. There is continuing debate with regard to the level of glycaemic control and the potential benefits of insulin therapy in both diabetic and non-diabetic patients undergoing cardiac surgery. This review article sets out to discuss the evidence for glycaemic control, as well as the potential benefits of insulin therapy in the form of glucose-insulin-potassium therapy in cardiac surgery.
Export Options
About this article
Cite this article as:
Menon Ashvini and Ranasinghe M. A., Insulin Therapy in Cardiac Surgery, Current Diabetes Reviews 2014; 10 (4) . https://dx.doi.org/10.2174/1573399810666140918120228
DOI https://dx.doi.org/10.2174/1573399810666140918120228 |
Print ISSN 1573-3998 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6417 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
The Molecular Concept of Atheromatous Plaques
Current Drug Targets PET Measurements of cAMP-Mediated Phosphodiesterase-4 with (R)-[11C]Rolipram
Current Radiopharmaceuticals AMI and Anabolic-Androgenic Steroids: Case Report with Systematic Review
Current Cardiology Reviews The Effects of Dietary Supplements that Overactivate the Nrf2/ARE System
Current Medicinal Chemistry Getting to the Heart of the Matter: Exploring Opportunities for Gene Therapy Treatment of Dystrophic Cardiomyopathy
Current Gene Therapy Novel Strategies for the Management of Acute Decompensated Heart Failure
Current Cardiology Reviews Pulmonary Hypertension and Systemic Diseases
Current Drug Targets - Inflammation & Allergy Editorial (Thematic Issue: Calcium in Heart Disease: The Ubiquitous Ion)
Medicinal Chemistry Vitamins in Heart Failure: Friend or Enemy?
Current Pharmaceutical Design Cardiac MRI in Infiltrative Disorders: A Concise Review
Current Cardiology Reviews Use of Clinically Available PPAR Agonists for Heart Failure; Do the Risks Outweigh the Potential Benefits?
Current Molecular Pharmacology Risk Profiles in Type 2 Diabetes (Metabolic Syndrome): Integration of IL-10 Polymorphisms and Laboratory Parameters to Identify Vascular Damages Related Complications
Current Pharmaceutical Design Insulin Resistance, Oxidative Stress and Cardiovascular Complications: Role of Sirtuins
Current Pharmaceutical Design Targeting SUMOylation Cascade for Diabetes Management
Current Drug Targets GRK2 and Beta-Arrestins in Cardiovascular Disease: Established and Emerging Possibilities for Therapeutic Targeting
Current Molecular Pharmacology Do Advanced Glycation End Products (AGEs) Contribute to the Comorbidities of Polycystic Ovary Syndrome (PCOS)?
Current Pharmaceutical Design Identification of Important Positions within miRNAs by Integrating Sequential and Structural Features
Current Protein & Peptide Science The Role of PPARβ/δ in the Management of Metabolic Syndrome and its Associated Cardiovascular Complications
Endocrine, Metabolic & Immune Disorders - Drug Targets Nitroso-Redox Balance and Modulation of Basal Myocardial Function: An Update from the Italian Society of Cardiovascular Research (SIRC)
Current Drug Targets Toll-Like Receptors and Human Disease: Lessons from Single Nucleotide Polymorphisms
Current Genomics