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Letters in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

Synthesis of Some New Pyrano[2,3-b]quinolines from 2-chloro-3- formylquinolones and Meldrum's Acid

Author(s): Fatiha Guenfoud, Raouf Boulcina, Mohammed Laabassi and Paul Mosset

Volume 11, Issue 10, 2014

Page: [736 - 742] Pages: 7

DOI: 10.2174/1570178611666140829214223

Price: $65

Abstract

A new series of functionalized pyrano[2,3-b]quinolines have been prepared in three steps from first condensation of 3-formyl-2-quinolones with Meldrum’s acid, then the corresponding olefins have been alkylated using methyl magnesium iodide, and finally the target compounds have been obtained in good yields after hydrolysis.

Keywords: 3-formyl-2-quinolones, knoevenagel condensation, meldrum’s acid, pyrano[2, 3-b]quinolines.

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