Abstract
Target of monoamine oxidase inhibitions are considered as the treatment of depressive states and neurodegenerative disorders, including Parkinson’s and Alzheimer’s diseases. Many medicinal chemistry research groups are actively working in this area for the development of most promising selective MAO inhibitors. Many plant isolates also showed remarkable MAO inhibition in recent years. The objective of this review is to identify the major MAO inhibitors secondary metabolites from plants like flavonoids, alkaloids and xanthones class of compounds.
Keywords: Alkaloids, flavonoids, monoamine oxidase inhibitors, xanthones.
Central Nervous System Agents in Medicinal Chemistry
Title:Plant Secondary Metabolites- Potent Inhibitors of Monoamine Oxidase Isoforms
Volume: 14 Issue: 1
Author(s): Bijo Mathew, Jerad Suresh, Githa E. Mathew, Ramamoorthy Parasuraman and Nalakathu Abdulla
Affiliation:
Keywords: Alkaloids, flavonoids, monoamine oxidase inhibitors, xanthones.
Abstract: Target of monoamine oxidase inhibitions are considered as the treatment of depressive states and neurodegenerative disorders, including Parkinson’s and Alzheimer’s diseases. Many medicinal chemistry research groups are actively working in this area for the development of most promising selective MAO inhibitors. Many plant isolates also showed remarkable MAO inhibition in recent years. The objective of this review is to identify the major MAO inhibitors secondary metabolites from plants like flavonoids, alkaloids and xanthones class of compounds.
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Cite this article as:
Mathew Bijo, Suresh Jerad, Mathew E. Githa, Parasuraman Ramamoorthy and Abdulla Nalakathu, Plant Secondary Metabolites- Potent Inhibitors of Monoamine Oxidase Isoforms, Central Nervous System Agents in Medicinal Chemistry 2014; 14 (1) . https://dx.doi.org/10.2174/1871524914666140826111930
DOI https://dx.doi.org/10.2174/1871524914666140826111930 |
Print ISSN 1871-5249 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6166 |
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