Abstract
MicroRNAs (miRNAs) are small noncoding regulatory RNAs that control essential cellular activities. Many viruses use these regulators to help infect host cells and maintain their presence in those cells. Therefore, virus-encoded miRNAs are important tools for viruses in the battle with their hosts. Knowledge of these miRNAs is essential for the development of new drugs to treat viral diseases and virus-associated cancers. In this minireview, the miRNAs encoded in viral genomes, their expression and functions, the interactions between viral and cellular miRNAs in viral diseases and virus- associated cancers, and the use of miRNAs for therapy are described.
Keywords: Cellular miRNA, expression, interaction, latent infection, lytic infection, viral miRNA, viruses.
MicroRNA
Title:MicroRNAs in Human Virus Genomes: Helping Hands for Viral Infection
Volume: 3 Issue: 2
Author(s): Ding-Gan Liu
Affiliation:
Keywords: Cellular miRNA, expression, interaction, latent infection, lytic infection, viral miRNA, viruses.
Abstract: MicroRNAs (miRNAs) are small noncoding regulatory RNAs that control essential cellular activities. Many viruses use these regulators to help infect host cells and maintain their presence in those cells. Therefore, virus-encoded miRNAs are important tools for viruses in the battle with their hosts. Knowledge of these miRNAs is essential for the development of new drugs to treat viral diseases and virus-associated cancers. In this minireview, the miRNAs encoded in viral genomes, their expression and functions, the interactions between viral and cellular miRNAs in viral diseases and virus- associated cancers, and the use of miRNAs for therapy are described.
Export Options
About this article
Cite this article as:
Liu Ding-Gan, MicroRNAs in Human Virus Genomes: Helping Hands for Viral Infection, MicroRNA 2014; 3 (2) . https://dx.doi.org/10.2174/2211536603666140825193447
DOI https://dx.doi.org/10.2174/2211536603666140825193447 |
Print ISSN 2211-5366 |
Publisher Name Bentham Science Publisher |
Online ISSN 2211-5374 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
The Use of Cytokines and Chemokines in the Cancer Immunotherapy
Recent Patents on Anti-Cancer Drug Discovery Synthesis, Molecular Docking Study and in vitro Anticancer Activity of Tetrazole Linked Benzochromene Derivatives
Anti-Cancer Agents in Medicinal Chemistry Microwave-Assisted Synthesis of Thiazole/Benzothiazole Fused Pyranopyrimidine Derivatives and Evaluation of their Biological Activity
Letters in Organic Chemistry Cellular Iron Homeostasis and Therapeutic Implications of Iron Chelators in Cancer
Current Pharmaceutical Biotechnology Versatility of Cancer Associated Fibroblasts: Commendable Targets for Anti-tumor Therapy
Current Drug Targets Sodium Lauryl Sulfate, a Microbicide Effective Against Enveloped and Nonenveloped Viruses
Current Drug Targets Juglone Exerts Cytotoxic, Anti-proliferative and Anti-invasive Effects on Glioblastoma Multiforme in a Cell Culture Model
Anti-Cancer Agents in Medicinal Chemistry Viral Origins of Human Cancer
Current Medicinal Chemistry Detection of Squamous Cell Carcinoma Antigen with Micro- and Nanogap Interdigitated Electrodes and Gold Nanoparticles
Micro and Nanosystems Evidence for Epigenetic Alterations in Turner Syndrome Opens up Feasibility of New Pharmaceutical Interventions
Current Pharmaceutical Design Anticancer Properties of Asian Water Monitor Lizard (Varanus salvator), Python (Malayopython reticulatus) and Tortoise (Cuora kamaroma amboinensis)
Anti-Cancer Agents in Medicinal Chemistry Radiation Therapy Plus Angiogenesis Inhibition with Bevacizumab: Rationale and Initial Experience
Reviews on Recent Clinical Trials Biogenic Synthesis of Silver Nanoparticles using Azadirachta indica (Neem) Leaf Extract To Achieve Inhibitory Action Against Antibiotic-Resistant Bacteria
Anti-Infective Agents Epi-Drugs and Epi-miRs: Moving Beyond Current Cancer Therapies
Current Cancer Drug Targets Can Diabetes Heal?- From Observations to Perspectives
Current Diabetes Reviews Estrogen-Related Receptors as Emerging Targets in Cancer and Metabolic Disorders
Current Topics in Medicinal Chemistry Editorial (Thematic Issue: Nanosystems: An Innovative Tools for Medicinal Chemistry)
Current Topics in Medicinal Chemistry Channel-Like Functions of the 18-kDa Translocator Protein (TSPO): Regulation of Apoptosis and Steroidogenesis as Part of the Host-Defense Response
Current Pharmaceutical Design Neurotoxic and Neuroactive Compounds from Cnidaria: Five Decades of Research….and More
Central Nervous System Agents in Medicinal Chemistry Macromolecular Drug Targets in Cancer Treatment and Thiosemicarbazides as Anticancer Agents
Anti-Cancer Agents in Medicinal Chemistry