Abstract
Advances in ‘omics’ high-throughput technologies have led to a vast amount and quality of available biological data. It has fostered the development of bioinformatics methods to interpret these data. In this regard, characterization of cellular metabolism is a useful task to understand the phenotypic capabilities of an organism. Several in silico approaches have emerged for analysis of metabolic pathways, including structural and stoichiometric analysis, metabolic flux analysis, metabolic control analysis, and several kinetic modeling based analysis. The present article provides the comprehensive survey on existing metabolic pathway analysis methodologies.
Keywords: Elementary flux mode analysis, extreme pathway analysis, flux balance analysis, metabolic pathway modeling.
Current Bioinformatics
Title:A Comprehensive View on Metabolic Pathway Analysis Methodologies
Volume: 9 Issue: 3
Author(s): Namrata Tomar and Rajat K. De
Affiliation:
Keywords: Elementary flux mode analysis, extreme pathway analysis, flux balance analysis, metabolic pathway modeling.
Abstract: Advances in ‘omics’ high-throughput technologies have led to a vast amount and quality of available biological data. It has fostered the development of bioinformatics methods to interpret these data. In this regard, characterization of cellular metabolism is a useful task to understand the phenotypic capabilities of an organism. Several in silico approaches have emerged for analysis of metabolic pathways, including structural and stoichiometric analysis, metabolic flux analysis, metabolic control analysis, and several kinetic modeling based analysis. The present article provides the comprehensive survey on existing metabolic pathway analysis methodologies.
Export Options
About this article
Cite this article as:
Tomar Namrata and De K. Rajat, A Comprehensive View on Metabolic Pathway Analysis Methodologies, Current Bioinformatics 2014; 9 (3) . https://dx.doi.org/10.2174/1574893609666140516005147
DOI https://dx.doi.org/10.2174/1574893609666140516005147 |
Print ISSN 1574-8936 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-392X |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
The Role of Heat Shock Protein (HSP) in Atherosclerosis: Pathophysiology and Clinical Opportunities
Current Medicinal Chemistry Using Metabolomics for Elucidating the Mechanisms Related to Tuberculosis Treatment Failure
Current Metabolomics New Targets, New Hope: Novel Drug Targets for Curbing Malaria
Mini-Reviews in Medicinal Chemistry Salicylanilide Ester Prodrugs as Potential Antimicrobial Agents - a Review
Current Pharmaceutical Design 1, 2, 4-triazoles Clubbed Pyrimidine Compounds with Synthesis, Antimicrobial, Antituberculosis, Antimalarial, and Anti-protozoal Studies
Letters in Organic Chemistry Synthesis and Antitubercular Evaluation of N-[(E)-(hydroxy, methoxy and ethoxy-substituted-phenyl) Methylidene]isonicotinohydrazide Derivatives
Letters in Drug Design & Discovery Innate Immunity, Toll-Like Receptors, and Diabetes
Current Immunology Reviews (Discontinued) Fracture Risk Associated with Use of Antibiotics
Current Drug Safety Reversal of Tumor Induced Dendritic Cell Paralysis: A Treatment Regimen Against Cancer
Current Immunology Reviews (Discontinued) Recent Advancement in Predicting Subcellular Localization of Mycobacterial Protein with Machine Learning Methods
Medicinal Chemistry Bacterial Resistance to Antimicrobial Host Defenses - An Emerging Target for Novel Antiinfective Strategies?
Current Drug Targets Malaria and artemisinin derivatives: an updated review
Mini-Reviews in Medicinal Chemistry Structure and Function of Bacterial Kid-Kis and Related Toxin-Antitoxin Systems
Protein & Peptide Letters Nanodelivery Systems for Mucosal Vaccines
Recent Patents on Nanomedicine Non Nucleoside Reverse Transcriptase Inhibitors, Molecular Docking Studies and Antitubercular Activity of Thiazolidin-4-one Derivatives
Current Computer-Aided Drug Design New Frontiers in the Therapy of Tuberculosis: Fighting with the Global Menace
Mini-Reviews in Medicinal Chemistry Pharmacologic Role of Vitamin D Natural Products
Current Vascular Pharmacology Regulation of Cytokine Production by γδ T Cells
Current Medicinal Chemistry - Anti-Inflammatory & Anti-Allergy Agents Recent Advances in Medicinal Chemistry to Treat Tuberculosis – Part-II
Current Topics in Medicinal Chemistry Vitamin D and Infectious Diseases
Endocrine, Metabolic & Immune Disorders - Drug Targets