Nanostructured Biomaterials with Antimicrobial Properties

Title:Nanostructured Biomaterials with Antimicrobial Properties

Volume: 21 Issue: 29

Author(s): Yesim Muge Sahin, Mehmet Yetmez, Faik N. Oktar, Oguzhan Gunduz, Simeon Agathopoulos, Ecaterina Andronescu, Denisa Ficai, Maria Sonmez and Anton Ficai

Affiliation:

Keywords: Antibiotics, antimicrobial agents, biomaterials, drug delivery systems, nano-materials, natural polymers, silver, zinc oxide.

Abstract: The present review is intended to bring together the main advances in the field of nanostructured biomaterials with antimicrobial properties. It is generally accepted that the discovery of antibiotics was of great importance but, nowadays new antimicrobial agents are needed and/or their better administration routes. The limitation of the use of antibiotics is essential because of the following reasons: the excessive use of antibiotics leads to the development of antibiotic resistant microorganisms; there are some alternatives for many types of infections, many of these alternatives being less toxic and do not lead to antibiotic similar resistance. In compliance with the above presented, the use of antibiotic is recommended to be eliminated (when alternatives are available) or to be reduced by using combined therapy when possible or to administrate these drugs through targeted or loco-regional drug delivery systems.

Cite this article as:

Sahin Muge Yesim, Yetmez Mehmet, Oktar N. Faik, Gunduz Oguzhan, Agathopoulos Simeon, Andronescu Ecaterina, Ficai Denisa, Sonmez Maria and Ficai Anton, Nanostructured Biomaterials with Antimicrobial Properties, Current Medicinal Chemistry 2014; 21 (29) . https://dx.doi.org/10.2174/0929867321666140304104950