Abstract
Due to the ability to differentiate into numerous cell types, multipotent mesenchymal stem cells (MSCs) are currently researched widely including in the field of craniofacial tissues engineering where always requires a wide variety of cell types and tissues while complete surgical reconstruction of craniofacial tissues is always difficult to achieve based on conventional therapies due to such high complexity. Nowadays, numerous animal model studies have been reported on the effect of MSCs in craniofacial tissue engineering including bone, tendon, cartilage, cutaneous wound and vascularization repair etc. Several clinical trials also have been reported with inspiring results. In this review, we will summarize the recent progress of MSCs in craniofacial tissue engineering and the potential clinical application in future.
Keywords: Adipose stem cells, craniofacial reconstruction, mesenchymal stem cells, tissue engineering.
Current Stem Cell Research & Therapy
Title:The Effects of Mesenchymal Stem Cells in Craniofacial Tissue Engineering
Volume: 9 Issue: 3
Author(s): Lin Zhang, Ge Feng, Xing Wei, Lan Huang, Aishu Ren, Ni Dong, Huaqiao Wang, Qianqian Huang, Yi Zhang and Feng Deng
Affiliation:
Keywords: Adipose stem cells, craniofacial reconstruction, mesenchymal stem cells, tissue engineering.
Abstract: Due to the ability to differentiate into numerous cell types, multipotent mesenchymal stem cells (MSCs) are currently researched widely including in the field of craniofacial tissues engineering where always requires a wide variety of cell types and tissues while complete surgical reconstruction of craniofacial tissues is always difficult to achieve based on conventional therapies due to such high complexity. Nowadays, numerous animal model studies have been reported on the effect of MSCs in craniofacial tissue engineering including bone, tendon, cartilage, cutaneous wound and vascularization repair etc. Several clinical trials also have been reported with inspiring results. In this review, we will summarize the recent progress of MSCs in craniofacial tissue engineering and the potential clinical application in future.
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Cite this article as:
Zhang Lin, Feng Ge, Wei Xing, Huang Lan, Ren Aishu, Dong Ni, Wang Huaqiao, Huang Qianqian, Zhang Yi and Deng Feng, The Effects of Mesenchymal Stem Cells in Craniofacial Tissue Engineering, Current Stem Cell Research & Therapy 2014; 9 (3) . https://dx.doi.org/10.2174/1574888X09666140213204202
DOI https://dx.doi.org/10.2174/1574888X09666140213204202 |
Print ISSN 1574-888X |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3946 |
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