Abstract
More and more studies indicate that the issue of protein-coding gene finding in microbial genomes is far from thoroughly solved and the annotation quality has been questioned continuously in the past several years. In this paper, we summarize the computational methods for identifying the over-annotated genes and missing genes, and provide perspective for prospective gene finding works.
Keywords: Microbial genome, missing gene, over-annotated gene, protein-coding gene, re-annotation.
Current Bioinformatics
Title:A Review of the Computational Methods for Identifying the Over- Annotated Genes and Missing Genes in Microbial Genomes
Volume: 9 Issue: 2
Author(s): Jia-Feng Yu, Zhen-Zhen Guo, Xiao Sun and Ji-Hua Wang
Affiliation:
Keywords: Microbial genome, missing gene, over-annotated gene, protein-coding gene, re-annotation.
Abstract: More and more studies indicate that the issue of protein-coding gene finding in microbial genomes is far from thoroughly solved and the annotation quality has been questioned continuously in the past several years. In this paper, we summarize the computational methods for identifying the over-annotated genes and missing genes, and provide perspective for prospective gene finding works.
Export Options
About this article
Cite this article as:
Yu Jia-Feng, Guo Zhen-Zhen, Sun Xiao and Wang Ji-Hua, A Review of the Computational Methods for Identifying the Over- Annotated Genes and Missing Genes in Microbial Genomes, Current Bioinformatics 2014; 9 (2) . https://dx.doi.org/10.2174/1574893608999140109120612
DOI https://dx.doi.org/10.2174/1574893608999140109120612 |
Print ISSN 1574-8936 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-392X |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Target Product Selection - Where Can Molecular Pharming Make the Difference?
Current Pharmaceutical Design Microwave-assisted Synthesis of Novel Triazolyl Pyrazolyl Pyrazoline Substituted Coumarins and Their Antimicrobial Activity
Current Microwave Chemistry Peptide Arrays for the Analysis of Antibody Epitope Recognition Patterns
Mini-Reviews in Organic Chemistry Streptococcal Collagen-like Protein 1 Binds Wound Fibronectin: Implications in Pathogen Targeting
Current Medicinal Chemistry Clinical Applications of Choline PET/CT in Brain Tumors
Current Pharmaceutical Design Patent Selections:
Recent Patents on Anti-Infective Drug Discovery From Conventional Reaction Conditions to Microwave-Assisted Catalytic Transformations of Various Substrates. State of the Art in 2012 (Part A: General)
Current Organic Chemistry Molecular Tools for Typing and Branding the Tubercle Bacillus
Current Molecular Medicine The Plant-Type Ferredoxin-NADP+ Reductase/Ferredoxin Redox System as a Possible Drug Target Against Apicomplexan Human Parasites
Current Pharmaceutical Design Targeting Host Factors to Circumvent Anti-Malarial Drug Resistance
Current Pharmaceutical Design Copper (II) – HisAibGly Complex and Its Superoxide Dismutase Activity (Suplementary Material)
Protein & Peptide Letters Characterizing the Binding of Angiotensin Converting Enzyme I Inhibitory Peptide to Human Hemoglobin: Influence of Electromagnetic Fields
Protein & Peptide Letters Pentapeptides as Minimal Functional Units in Cell Biology and Immunology
Current Protein & Peptide Science Preface
Recent Patents on Anti-Infective Drug Discovery P2X Receptors and Inflammation
Current Medicinal Chemistry Editorial (Thematic Issue: <i>In Silico</i> Drug Design and Medicinal Chemistry)
Current Topics in Medicinal Chemistry Lactosylceramide is a Pattern Recognition Receptor that Forms Lyn-Coupled Membrane Microdomains on Neutrophils
Immunology, Endocrine & Metabolic Agents in Medicinal Chemistry (Discontinued) Recent Updates on Applications of Lipid-Based Nanoparticles for Site- Specific Drug Delivery
Pharmaceutical Nanotechnology Role of Sulfur Containing Amino Acids as an Adjuvant Therapy in the Prevention of Diabetes and its Associated Complications
Current Diabetes Reviews Exacerbations of Asthma and Chronic Obstructive Pulmonary Disease (COPD): Focus on Virus Induced Exacerbations
Current Pharmaceutical Design