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Current Pharmaceutical Design

Editor-in-Chief

ISSN (Print): 1381-6128
ISSN (Online): 1873-4286

Toward a Better Understanding of Pharmacokinetics of Nanomaterials

Author(s): Chengke Zhang, Qiu Zhang, Yi Zhang and Bing Yan

Volume 19, Issue 37, 2013

Page: [6667 - 6680] Pages: 14

DOI: 10.2174/1381612811319370010

Price: $65

Abstract

Nanotechnology has promising applications in biomedicine, such as in drug delivery, diagnosis, and tissue engineering. The pharmacokinetics of nanomaterials significantly affects their biological behavior in vivo, affecting their biomedical applications and potential nanotoxicity. In this review, we highlight some recent advances in the pharmacokinetic studies of representative nanomaterials. We focus on the relationships between the physicochemical properties of nanomaterials and physiological consequences.

Keywords: Nanomaterials, pharmacokinetics, absorption, distribution, metabolism, excretion.


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