Nanocarrier based Antiretroviral Drug Delivery Approaches

Sakshi      Taneja; Kapil      Khatri

Abstract

With the aim to reduce dosing frequency and to target drugs to cellular compartments actually in need of treatment, the design of drug delivery systems is becoming complementary to new drug discovery. The review highlights various drug/antigen delivery approaches comprising of vesicular and particulate nanocarriers that are associated with spectacular advantages like improved solubility and stability for poorly soluble drugs, good safety profile, versatility for encapsulating nearly all drugs, drug-release modulation, high drug payloads etc. In this review, light is shed on the remarkable potential of nanotechnology to provide more effective therapeutic and prophylactic approaches for the treatment and prevention for HIV/AIDS.

Keywords: Antiretroviral, drug delivery, nanocarriers, particulate drug delivery, vesicular drug delivery.

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