Abstract
In the last few decades, a lot of work has been done on heterocycles, especially the imidazole ring, to obtain a scaffold with potential pharmacological properties such as antibacterial, antifungal, anticancer, antiviral, antidiabetic and others, with lesser side effects. The search for new biologically active imidazoles continues to be an interesting area of investigation in medicinal chemistry. The present paper aims to bring together and discuss the wealth of information on antibacterial profile of imidazoles. So it can be employed for future development to obtain new potent drug molecules.
Keywords: Bacteria, Antibacterial agent, Imidazole, Structure activity relationship study.
Mini-Reviews in Medicinal Chemistry
Title:Imidazoles as Promising Scaffolds for Antibacterial Activity: A Review
Volume: 13 Issue: 12
Author(s): Nidhi Rani, Ajay Sharma and Randhir Singh
Affiliation:
Keywords: Bacteria, Antibacterial agent, Imidazole, Structure activity relationship study.
Abstract: In the last few decades, a lot of work has been done on heterocycles, especially the imidazole ring, to obtain a scaffold with potential pharmacological properties such as antibacterial, antifungal, anticancer, antiviral, antidiabetic and others, with lesser side effects. The search for new biologically active imidazoles continues to be an interesting area of investigation in medicinal chemistry. The present paper aims to bring together and discuss the wealth of information on antibacterial profile of imidazoles. So it can be employed for future development to obtain new potent drug molecules.
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Cite this article as:
Rani Nidhi, Sharma Ajay and Singh Randhir, Imidazoles as Promising Scaffolds for Antibacterial Activity: A Review, Mini-Reviews in Medicinal Chemistry 2013; 13 (12) . https://dx.doi.org/10.2174/13895575113136660091
DOI https://dx.doi.org/10.2174/13895575113136660091 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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