Generic placeholder image

Mini-Reviews in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

Imidazoles as Potential Antifungal Agents: A Review

Author(s): Nidhi Rani, Ajay Sharma, Girish Kumar Gupta and Randhir Singh

Volume 13, Issue 11, 2013

Page: [1626 - 1655] Pages: 30

DOI: 10.2174/13895575113139990069

Price: $65

Abstract

Imidazoles are one of the most promising and vigorously pursued areas of contemporary antifungal chemotherapy depicting broad spectrum and potent activity. They have relatively simple molecular nucleus, which is amenable to many structural modifications. These agents have several favorable properties such as excellent bioavailability, good tissue penetrability and permeability and a relatively low incidence of adverse and toxic effects. They have been found effective in the treatment of various infectious diseases. This paper is an attempt to review the therapeutic potential of imidazoles as antifungal with an updated account on their development.

Keywords: Antifungal agent, Antimycotic agent, Imidazole, Structure-Activity Relationship study.


Rights & Permissions Print Cite
© 2024 Bentham Science Publishers | Privacy Policy