Abstract
The Acute Respiratory Distress Syndrome (ARDS) is a highly fatal pro-inflammatory oxidative respiratory disease. Relatively recently, the modulating effects of chronic inflammatory processes on ARDS susceptibility have been recognized in a number of clinical studies. Herein, we briefly review some of the chronic conditions that have been reported to increase (cigarette smoking and alcohol abuse) or decrease (diabetes and obesity) susceptibility to ARDS. We also propose some potential pathways that may hold clues regarding the pathogenesis and/or therapy for ARDS.
Keywords: ARDS, susceptibility, modulation, chronic inflammation.
Current Pharmaceutical Design
Title:Chronic Inflammatory Diseases and the Acute Respiratory Distress Syndrome (ARDS)
Volume: 20 Issue: 9
Author(s): Ana Fernandez-Bustamante and John E. Repine
Affiliation:
Keywords: ARDS, susceptibility, modulation, chronic inflammation.
Abstract: The Acute Respiratory Distress Syndrome (ARDS) is a highly fatal pro-inflammatory oxidative respiratory disease. Relatively recently, the modulating effects of chronic inflammatory processes on ARDS susceptibility have been recognized in a number of clinical studies. Herein, we briefly review some of the chronic conditions that have been reported to increase (cigarette smoking and alcohol abuse) or decrease (diabetes and obesity) susceptibility to ARDS. We also propose some potential pathways that may hold clues regarding the pathogenesis and/or therapy for ARDS.
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Cite this article as:
Fernandez-Bustamante Ana and Repine E. John, Chronic Inflammatory Diseases and the Acute Respiratory Distress Syndrome (ARDS), Current Pharmaceutical Design 2014; 20 (9) . https://dx.doi.org/10.2174/13816128113199990561
DOI https://dx.doi.org/10.2174/13816128113199990561 |
Print ISSN 1381-6128 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4286 |
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