Abstract
Diabetic retinopathy affects one-third of people with diabetes and is the most frequent cause of blindness in working aged adults. Although diabetic retinopathy blindness appears to have fallen in the developed world, the rapidly increasing number of persons with diabetes worldwide has resulted in a continuous increase in the global burden of this disease. The major risk factors for diabetic retinopathy include duration of diabetes, hyperglycemia, and hypertension, but this is accountable for only a small amount of the variation in the risk of diabetic retinopathy. Research into new markers for retinopathy including genetics, blood biomarkers and retinal imaging will further improve our understanding of the risk factors and pathogenesis of diabetic retinopathy.
Keywords: Diabetic retinopathy, epidemiology, genetics, biological markers, risk factors.
Current Medicinal Chemistry
Title:Traditional and Novel Risk Factors of Diabetic Retinopathy and Research Challenges
Volume: 20 Issue: 26
Author(s): Gavin S. Tan, M. Kamran Ikram and Tien Y. Wong
Affiliation:
Keywords: Diabetic retinopathy, epidemiology, genetics, biological markers, risk factors.
Abstract: Diabetic retinopathy affects one-third of people with diabetes and is the most frequent cause of blindness in working aged adults. Although diabetic retinopathy blindness appears to have fallen in the developed world, the rapidly increasing number of persons with diabetes worldwide has resulted in a continuous increase in the global burden of this disease. The major risk factors for diabetic retinopathy include duration of diabetes, hyperglycemia, and hypertension, but this is accountable for only a small amount of the variation in the risk of diabetic retinopathy. Research into new markers for retinopathy including genetics, blood biomarkers and retinal imaging will further improve our understanding of the risk factors and pathogenesis of diabetic retinopathy.
Export Options
About this article
Cite this article as:
Tan S. Gavin, Ikram Kamran M. and Wong Y. Tien, Traditional and Novel Risk Factors of Diabetic Retinopathy and Research Challenges, Current Medicinal Chemistry 2013; 20 (26) . https://dx.doi.org/10.2174/09298673113209990023
DOI https://dx.doi.org/10.2174/09298673113209990023 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
Call for Papers in Thematic Issues
Advances in Medicinal Chemistry: From Cancer to Chronic Diseases.
The broad spectrum of the issue will provide a comprehensive overview of emerging trends, novel therapeutic interventions, and translational insights that impact modern medicine. The primary focus will be diseases of global concern, including cancer, chronic pain, metabolic disorders, and autoimmune conditions, providing a broad overview of the advancements in ...read more
Approaches to the treatment of chronic inflammation
Chronic inflammation is a hallmark of numerous diseases, significantly impacting global health. Although chronic inflammation is a hot topic, not much has been written about approaches to its treatment. This thematic issue aims to showcase the latest advancements in chronic inflammation treatment and foster discussion on future directions in this ...read more
Cellular and Molecular Mechanisms of Non-Infectious Inflammatory Diseases: Focus on Clinical Implications
The Special Issue covers the results of the studies on cellular and molecular mechanisms of non-infectious inflammatory diseases, in particular, autoimmune rheumatic diseases, atherosclerotic cardiovascular disease and other age-related disorders such as type II diabetes, cancer, neurodegenerative disorders, etc. Review and research articles as well as methodology papers that summarize ...read more
Chalcogen-modified nucleic acid analogues
Chalcogen-modified nucleosides, nucleotides and oligonucleotides have been of great interest to scientific research for many years. The replacement of oxygen in the nucleobase, sugar or phosphate backbone by chalcogen atoms (sulfur, selenium, tellurium) gives these biomolecules unique properties resulting from their altered physical and chemical properties. The continuing interest in ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Recent Advances in the Characterization of Genetic Factors Involved in Human Susceptibility to Infection by Schistosomiasis
Current Genomics Fractional Flow Reserve: Physiological Basis, Advantages and Limitations, and Potential Gender Differences
Current Cardiology Reviews Perivascular Adipose Tissue as an Endocrine Organ: The Role of Statins
Current Pharmaceutical Design Role of Vascular Progenitor Cells in Cardiovascular Disease
Current Pharmaceutical Design Enhanced Risk for Specific Somatic Myeloproliferative Neoplastic Mutations in Patients with Stroke
Current Neurovascular Research Cardiac and Metabolic Consequences of Aerobic Exercise Training in Experimental Diabetes
Current Diabetes Reviews Mediterranean Diet and Oxidation: Nuts and Olive Oil as Important Sources of Fat and Antioxidants
Current Topics in Medicinal Chemistry Mechanism Underlying the Formation of a Cluster of Metabolic Syndrome
Endocrine, Metabolic & Immune Disorders - Drug Targets Molecular Diagnosis and Treatment of Multiple Endocrine Neoplasia Type 2B in Ethnic Han Chinese
Endocrine, Metabolic & Immune Disorders - Drug Targets Regulators of Platelet cAMP Levels: Clinical and Therapeutic Implications
Current Medicinal Chemistry New Designer Drugs (Synthetic Cannabinoids and Synthetic Cathinones): Review of Literature
Current Pharmaceutical Design Biomarkers in Atrial Fibrillation; From Pathophysiology to Diagnosis and Treatment
Current Medicinal Chemistry Effects of Metabolic Approach in Diabetic Patients with Coronary Artery Disease
Current Pharmaceutical Design Angiogenesis and Microvasculature in the Female Reproductive Organs: Physiological and Pathological Implications
Current Pharmaceutical Design Blood Pressure and Vascular Alterations with Growth in Childhood
Current Pharmaceutical Design Coenzyme Q10 Reduction with Statins: Another Pleiotropic Effect
Current Drug Therapy Patents in Oxidative Stress in Preeclampsia
Recent Patents on Biomarkers The NOX1/4 Inhibitor GKT136901 as Selective and Direct Scavenger of Peroxynitrite
Current Medicinal Chemistry Tolerability of Amine Uptake Inhibitors in Urologic Diseases
Current Drug Safety Postmenopausal Hypertension: Insights from Rat Models
Current Hypertension Reviews