Abstract
Much attention has been focused on cell-free DNA (cf-DNA) and its levels in the plasma, serum and body fluids of pregnant women and patients with cancer or autoimmune disease, and those with severe trauma; however, knowledge of its biology and relationship with myocardial infarction (MI) is still at an early stage. This paper introduces general aspects of the nomenclature, structure, function, release mechanisms and methodology of cf-DNA and summarizes the current literature on concentration variation and regulatory mechanisms in MI.
Keywords: Cell-free DNA, biological characteristics, methodology, myocardial infarction.
Current Pharmaceutical Design
Title:Cell-free DNA: Characteristics, Detection and its Applications in Myocardial Infarction
Volume: 19 Issue: 28
Author(s): Rongrong Jing, Ming Cui, Huimin Wang and Shaoqing Ju
Affiliation:
Keywords: Cell-free DNA, biological characteristics, methodology, myocardial infarction.
Abstract: Much attention has been focused on cell-free DNA (cf-DNA) and its levels in the plasma, serum and body fluids of pregnant women and patients with cancer or autoimmune disease, and those with severe trauma; however, knowledge of its biology and relationship with myocardial infarction (MI) is still at an early stage. This paper introduces general aspects of the nomenclature, structure, function, release mechanisms and methodology of cf-DNA and summarizes the current literature on concentration variation and regulatory mechanisms in MI.
Export Options
About this article
Cite this article as:
Jing Rongrong, Cui Ming, Wang Huimin and Ju Shaoqing, Cell-free DNA: Characteristics, Detection and its Applications in Myocardial Infarction, Current Pharmaceutical Design 2013; 19 (28) . https://dx.doi.org/10.2174/1381612811319280012
DOI https://dx.doi.org/10.2174/1381612811319280012 |
Print ISSN 1381-6128 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4286 |
Call for Papers in Thematic Issues
"Tuberculosis Prevention, Diagnosis and Drug Discovery"
The Nobel Prize-winning discoveries of Mycobacterium tuberculosis and streptomycin have enabled an appropriate diagnosis and an effective treatment of tuberculosis (TB). Since then, many newer diagnosis methods and drugs have been saving millions of lives. Despite advances in the past, TB is still a leading cause of infectious disease mortality ...read more
Current Pharmaceutical challenges in the treatment and diagnosis of neurological dysfunctions
Neurological dysfunctions (MND, ALS, MS, PD, AD, HD, ALS, Autism, OCD etc..) present significant challenges in both diagnosis and treatment, often necessitating innovative approaches and therapeutic interventions. This thematic issue aims to explore the current pharmaceutical landscape surrounding neurological disorders, shedding light on the challenges faced by researchers, clinicians, and ...read more
Emerging and re-emerging diseases
Faced with a possible endemic situation of COVID-19, the world has experienced two important phenomena, the emergence of new infectious diseases and/or the resurgence of previously eradicated infectious diseases. Furthermore, the geographic distribution of such diseases has also undergone changes. This context, in turn, may have a strong relationship with ...read more
Melanoma and Non-Melanoma Skin Cancer Treatment: Standard of Care and Recent Advances
In this thematic issue, we aim to provide a standard of care of the diagnosis and treatment of melanoma and non-melanoma skin cancer. The editor will invite authors from different countries who will write review articles of melanoma and non-melanoma skin cancers. The Diagnosis, Staging, Surgical Treatment, Non-Surgical Treatment all ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Exosomes: The Messengers of Health and Disease
Current Neuropharmacology Targeting Transient Receptor Potential Channels in Cardiometabolic Diseases and Myocardial Ischemia Reperfusion Injury
Current Drug Targets Disruption of Circadian Rhythms and Sleep on Critical Illness and the Impact on Cardiovascular Events
Current Pharmaceutical Design Editorial (Thematic Issue: Therapeutic Interventions Against Trypanosomiasis)
Current Topics in Medicinal Chemistry Dystroglycan, A Multifunctional Adaptor Protein for Signal Transduction and A Potential Therapeutic Target
Current Signal Transduction Therapy Dyslipidaemia Related to Insulin Resistance and Cardiovascular Disease in South Asian and West African Populations
Current Pharmaceutical Design Potential of Resveratrol in Preventing the Development of Heart Failure
Current Chemical Biology Oxidative-Nitrosative Stress In Hypertension
Current Vascular Pharmacology The Failing Heart in Pediatric Dilated Cardiomyopathy Caused by Excessive Water Drinking: A Case Report and Brief Review
New Emirates Medical Journal Proteomics to Identify Novel Biomarkers and Therapeutic Targets in Cardiovascular Disease
Letters in Drug Design & Discovery Irbesartan: Second Generation of ARB as Metabosartan
Current Hypertension Reviews Diabetes Mellitus: Channeling Care through Cellular Discovery
Current Neurovascular Research Induction of Myocardial Fibrosis and Hypertrophy by Natriuretic Peptides
Vascular Disease Prevention (Discontinued) Endocarditis Due to Salmonella Enterica Subsp. Arizonae in a Patient with Sickle Cell Disease: A Case Report and Review of the Literature
Cardiovascular & Hematological Disorders-Drug Targets Pegylated Liposomal Doxorubicin in Salvage Chemotherapy for Multiple Myeloma Patients
Current Cancer Therapy Reviews PET Imaging and Coronary Circulatory Function: Non-Invasive Mechanistic Insights and Cardiovascular Prognosis
Current Cardiology Reviews Adrenomedullin: Roles for Structure and Function in Cardiac or Vascular Tissues
Current Hypertension Reviews Diamidine Activity Against Trypanosomes: The State of the Art
Current Molecular Pharmacology Renin--Angiotensin System Gene Polymorphism and Regression of Left Ventricular Hypertrophy in Hypertension
Current Pharmacogenomics Possible Involvement of TRP Channels in Cardiac Hypertrophy and Arrhythmia
Current Topics in Medicinal Chemistry