Abstract
Vitamin D is essential for maintaining a healthy mineral and bone metabolism. It stimulates calcium and phosphate absorption by the intestine, regulates bone metabolism, and negatively controls PTH secretion through the endocrine action of its active metabolite calcitriol. Vitamin D also possesses a variety of effects unrelated with mineral and bone metabolism, including the regulation of arterial blood pressure and the prevention of cardiovascular complications, modulation of immunological responses, regulation of insulin production and prevention against diabetes, protection against certain cancers, renoprotection, and other beneficial actions. This article provides an update review of the sources and pharmacological characteristics of natural vitamin D compounds, their most clinical uses, and their most important clinical results.
Keywords: Bone, calcitriol, calcium, calcifediol, cholecalciferol, ergocalciferol, parathyroid hormone, phosphate.
Current Vascular Pharmacology
Title:Pharmacologic Role of Vitamin D Natural Products
Volume: 12 Issue: 2
Author(s): Pablo Urena-Torres and Jean Claude Souberbielle
Affiliation:
Keywords: Bone, calcitriol, calcium, calcifediol, cholecalciferol, ergocalciferol, parathyroid hormone, phosphate.
Abstract: Vitamin D is essential for maintaining a healthy mineral and bone metabolism. It stimulates calcium and phosphate absorption by the intestine, regulates bone metabolism, and negatively controls PTH secretion through the endocrine action of its active metabolite calcitriol. Vitamin D also possesses a variety of effects unrelated with mineral and bone metabolism, including the regulation of arterial blood pressure and the prevention of cardiovascular complications, modulation of immunological responses, regulation of insulin production and prevention against diabetes, protection against certain cancers, renoprotection, and other beneficial actions. This article provides an update review of the sources and pharmacological characteristics of natural vitamin D compounds, their most clinical uses, and their most important clinical results.
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Cite this article as:
Urena-Torres Pablo and Souberbielle Claude Jean, Pharmacologic Role of Vitamin D Natural Products, Current Vascular Pharmacology 2014; 12 (2) . https://dx.doi.org/10.2174/15701611113119990020
DOI https://dx.doi.org/10.2174/15701611113119990020 |
Print ISSN 1570-1611 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6212 |
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