Abstract
The research and development of calixarenes, cyclodextrins and fullerenes, which constitute the major classes of supramolecular organic host compounds, have been quite rapidly developing, increasingly active and newly rising highlight interdisciplinary fields. Numerous efforts have been directed toward such molecules as new platforms for anti- HIV drug design. This work briefly reviewed the recent development of calixarenes, cyclodextrins and fullerenes as new chemical entities of distinct anti-HIV activities. It is hoped that this review will serve as a stimulant for new thoughts in the quest for rational designs of more active and less toxic biological molecules as anti-HIV drugs.
Keywords: Drug design, anti-HIV, new platform, calixarene, cyclodextrin, fullerene.
Mini-Reviews in Medicinal Chemistry
Title:Development of Calixarenes, Cyclodextrins and Fullerenes as New Platforms for Anti-HIV Drug Design: An Overview
Volume: 13 Issue: 8
Author(s): Zaigang Luo, Xuemei Xu, Xiaomei Zhang and Liming Hu
Affiliation:
Keywords: Drug design, anti-HIV, new platform, calixarene, cyclodextrin, fullerene.
Abstract: The research and development of calixarenes, cyclodextrins and fullerenes, which constitute the major classes of supramolecular organic host compounds, have been quite rapidly developing, increasingly active and newly rising highlight interdisciplinary fields. Numerous efforts have been directed toward such molecules as new platforms for anti- HIV drug design. This work briefly reviewed the recent development of calixarenes, cyclodextrins and fullerenes as new chemical entities of distinct anti-HIV activities. It is hoped that this review will serve as a stimulant for new thoughts in the quest for rational designs of more active and less toxic biological molecules as anti-HIV drugs.
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Cite this article as:
Luo Zaigang, Xu Xuemei, Zhang Xiaomei and Hu Liming, Development of Calixarenes, Cyclodextrins and Fullerenes as New Platforms for Anti-HIV Drug Design: An Overview, Mini-Reviews in Medicinal Chemistry 2013; 13 (8) . https://dx.doi.org/10.2174/1389557511313080004
DOI https://dx.doi.org/10.2174/1389557511313080004 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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