Efficient Synthesis of Aromatic Nitriles via Cyanation of Aryl Bromides and K₄[Fe(CN)₆] Catalyzed by a Palladium(II) Complex

Title:Efficient Synthesis of Aromatic Nitriles via Cyanation of Aryl Bromides and K₄[Fe(CN)₆] Catalyzed by a Palladium(II) Complex

Volume: 10 Issue: 3

Author(s): Mengping Guo, Junying Ge, Zhiyong Zhu and Xiaochun Wu

Affiliation:

Keywords: Aromatic nitriles, cyanation, palladium(II) complex, synthesis

Abstract: Cyanation of aryl bromides and K₄[Fe(CN)₆] were carried out in the presence of catalytic amounts of {[(PhCH₂O)₂P(CH₃)₂CHNCH(CH₃)₂]₂PdCl₂} (PdCl₂L₂) in DMF and a variety of Aromatic nitriles were obtained in good yields under aerobic conditions.

Cite this article as:

Guo Mengping, Ge Junying, Zhu Zhiyong and Wu Xiaochun, Efficient Synthesis of Aromatic Nitriles via Cyanation of Aryl Bromides and K₄[Fe(CN)₆] Catalyzed by a Palladium(II) Complex, Letters in Organic Chemistry 2013; 10 (3) . https://dx.doi.org/10.2174/1570178611310030013