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Combinatorial Chemistry & High Throughput Screening

Editor-in-Chief

ISSN (Print): 1386-2073
ISSN (Online): 1875-5402

KF/Clinoptilolite: An Efficient Promoter for the Synthesis of Thioethers

Author(s): Sadegh Salmanpour, Mohammad A. Khalilzadeh and Abolfazl Hosseini

Volume 16, Issue 5, 2013

Page: [339 - 344] Pages: 6

DOI: 10.2174/1386207311316050002

Price: $65

Abstract

Potassium fluoride impregnated on natural zeolite as a new solid base system effectively catalyzes the coupling of thiophenols with electron-deficient fluoro-, chloro- and bromo-arenes in DMSO. This versatile and efficient solid base has been demonstrated to afford the corresponding desired products in good to excellent yields. This procedure provides a convenient, efficient and practical method for the preparation of diaryl thioethers.

Keywords: Diaryl thioethers, KF/clinoptilolite, natural zeolite, thiophenols.


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