Abstract
Ethnopharmacological relevance: In the traditional system of medicine, the plant Capparis decidua is well known for curing a variety of ailments such as toothache, cough, asthma, intermittent fever, rheumatism and inflammation.
Aim of the study: The aim of the current study was to isolate and characterize the constituent responsible for the antimicrobial activity of the ethanolic extract of C decidua.
Materials and methods: The isolated compound was extracted from ethanolic extract & characterized by spectroscopic methods. The antimicrobial activity of isolated compound was carried out against gram positive strains (S aureus, M luteus, B subtilus) and gram negative ones (P aeruginosa, E coli), and Fungi like C albicans and A niger by the cup-plate assay method and minimum inhibitory concentrations (MICs).
Results: The active principle Oleiyl glucoside (n-octadec-9-enyl- β-D- glucopyranoside) was isolated from the ethanolic extract. The MIC values of the compound against gram positive bacteria were 62.5μg/ml, 62.5 μg/ml, 125μg/ml and against gram negative ones 31.25μg/ml, 250μg/ml. The compound was found to be active against C albicans 250 μg/ml only.
Conclusions: The isolated compound Oleiyl glucoside showed moderate activity against bacteria and fungi.
Keywords: Capparis decidua, antibacterial, antifungal, oleiyl glucosides
The Natural Products Journal
Title:Antimicrobial Activity of Oleiyl Glucoside Isolated from the Traditional Medicinal Plant, Capparis decidua
Volume: 3 Issue: 1
Author(s): Sushila Rathee, Permender Rathee, Dharmender Rathee and Deepti Rathee
Affiliation:
Keywords: Capparis decidua, antibacterial, antifungal, oleiyl glucosides
Abstract: Ethnopharmacological relevance: In the traditional system of medicine, the plant Capparis decidua is well known for curing a variety of ailments such as toothache, cough, asthma, intermittent fever, rheumatism and inflammation.
Aim of the study: The aim of the current study was to isolate and characterize the constituent responsible for the antimicrobial activity of the ethanolic extract of C decidua.
Materials and methods: The isolated compound was extracted from ethanolic extract & characterized by spectroscopic methods. The antimicrobial activity of isolated compound was carried out against gram positive strains (S aureus, M luteus, B subtilus) and gram negative ones (P aeruginosa, E coli), and Fungi like C albicans and A niger by the cup-plate assay method and minimum inhibitory concentrations (MICs).
Results: The active principle Oleiyl glucoside (n-octadec-9-enyl- β-D- glucopyranoside) was isolated from the ethanolic extract. The MIC values of the compound against gram positive bacteria were 62.5μg/ml, 62.5 μg/ml, 125μg/ml and against gram negative ones 31.25μg/ml, 250μg/ml. The compound was found to be active against C albicans 250 μg/ml only.
Conclusions: The isolated compound Oleiyl glucoside showed moderate activity against bacteria and fungi.
Export Options
About this article
Cite this article as:
Rathee Sushila, Rathee Permender, Rathee Dharmender and Rathee Deepti, Antimicrobial Activity of Oleiyl Glucoside Isolated from the Traditional Medicinal Plant, Capparis decidua, The Natural Products Journal 2013; 3 (1) . https://dx.doi.org/10.2174/2210315511303010010
DOI https://dx.doi.org/10.2174/2210315511303010010 |
Print ISSN 2210-3155 |
Publisher Name Bentham Science Publisher |
Online ISSN 2210-3163 |
Call for Papers in Thematic Issues
Ayurvedic medicinal therapeutic approaches for inflammatory and neurodegenerative disorders
Usually, in our elderly population, neurodegenerative disorders occur due to neuron death. Alzheimer?s disease (AD) is an irreversible and progressive neurodegenerative disease. Dementia is the leading cause of AD, which affects about 30 million people worldwide. According to the World Alzheimer report 2018, a new case of dementia develops every ...read more
Recent Advances in Biotransformation of Bioactive Terpenoids using Aspergillus niger
Biotransformation is the reaction catalyzed by biological catalysts of either isolated enzymes or whole cell cultures of microorganisms. This process has been extensively applied in the conversion of bioactive terpenoids with high regio- and stereospecifity. This process has been also applied in the lead discovery and development. Aspergillus niger has ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Expression Levels of MicroRNA-125b in Serum Exosomes of Patients with Asthma of Different Severity and its Diagnostic Significance
Current Drug Metabolism Involvement of Cysteine Protease Inhibitors in the Defense Mechanism Against Parasites
Medicinal Chemistry Oral Tolerance and TGF-β -Producing Cells
Inflammation & Allergy - Drug Targets (Discontinued) Abundance and Diversity of GI Microbiota Rather than IgG<sub>4</sub> Levels Correlate with Abdominal Inconvenience and Gut Permeability in Consumers Claiming Food Intolerances
Endocrine, Metabolic & Immune Disorders - Drug Targets A Review of Flavonoids from Cassia Species and their Biological Activity
Current Pharmaceutical Biotechnology Mechanism of Idiosyncratic Drug Reactions: Reactive Metabolites Formation, Protein Binding and the Regulation of the Immune System
Current Drug Metabolism The Nitric Oxide View: Perspectives and Applications
Current Medicinal Chemistry Platelets and Vascular Risk: An Option for Treatment
Current Pharmaceutical Design Anatomical and Functional Relationships Between Sensory Nerves and Mast Cells
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry Designed Multiple Ligands: Basic Research vs Clinical Outcomes
Current Medicinal Chemistry Inotropic and Vasoactive Drugs in Pediatric ICU
Current Drug Targets Drugs that Target Lipoxygenases and Leukotrienes as Emerging Therapies for Asthma and Cancer
Current Drug Targets - Inflammation & Allergy The Impact of Combinatorial Methodologies on Medicinal Chemistry
Current Topics in Medicinal Chemistry Inhibition of Histone Deacetylases: A Pharmacological Approach to the Treatment of Non-Cancer Disorders
Current Topics in Medicinal Chemistry Metalloproteinases and Metalloproteinase Inhibitors in Age-Related Diseases
Current Pharmaceutical Design Patent Selections:
Recent Patents on Endocrine, Metabolic & Immune Drug Discovery Editorial [Hot Topic: Protein Kinase Inhibitors for the Treatment of Inflammatory Disease (Guest Editor: Mark R. Player)]
Current Topics in Medicinal Chemistry Non-Reproductive Effects of Sex Steroids: Their Immunoregulatory Role
Current Topics in Medicinal Chemistry Occupational Exposure and Occupational Asthma: Difference in Practices in Developed Countries v/s Developing Countries
Current Respiratory Medicine Reviews Updates on Aldose Reductase Inhibitors for Management of Diabetic Complications and Non-diabetic Diseases
Mini-Reviews in Medicinal Chemistry