Abstract
In this work, the capability of a hybrid tandem technique of LCMS-IT-TOF was examined for speciation of tripropyltin (TPrT), tributyltin (TBT), tripentyltin (TPeT) and triphenyltin (TPhT) and a relatively fast and accurate method was developed for their determination in aqueous solutions. In this context, several chromatographic parameters were studied such as chromatographic column, mobile phase, flow rate and gradient program in order to optimise the separation of the above species. Optimum separation was achieved using reverse phase C18 bonded-silica column. The mobile phase consisted of water and methanol and acetic acid at a total flow rate of 0.4 mL min–1 and the separation was completed in less than 8 min. Determination of the analytes was performed based on the signal of characteristic ions for each particular triorgano-tin compound. The detection limits of the set of the above four triorgano-tin species were ranged between 13 – 45 pg as absolute mass of Sn injected into the column and the relative standard deviation was ranged between 4.3 – 9.9 %. Finally, the performance characteristics of the method were compared to those reported in literature using similar tandem LC-MS techniques.
Keywords: HPLC, TOF-MS, triorgano-tin, speciation, tripropyltin, tributyltin, tripentyltin, triphenyltin
Current Analytical Chemistry
Title:Speciation Study of Trialkyl- and Triphenyl- Tin by Liquid Chromatography Using Ion Trap TOF Tandem MS and Atmospheric Pressure Chemical Ionization
Volume: 9 Issue: 2
Author(s): N. M. Tzollas, G. A. Zachariadis and E. Rosenberg
Affiliation:
Keywords: HPLC, TOF-MS, triorgano-tin, speciation, tripropyltin, tributyltin, tripentyltin, triphenyltin
Abstract: In this work, the capability of a hybrid tandem technique of LCMS-IT-TOF was examined for speciation of tripropyltin (TPrT), tributyltin (TBT), tripentyltin (TPeT) and triphenyltin (TPhT) and a relatively fast and accurate method was developed for their determination in aqueous solutions. In this context, several chromatographic parameters were studied such as chromatographic column, mobile phase, flow rate and gradient program in order to optimise the separation of the above species. Optimum separation was achieved using reverse phase C18 bonded-silica column. The mobile phase consisted of water and methanol and acetic acid at a total flow rate of 0.4 mL min–1 and the separation was completed in less than 8 min. Determination of the analytes was performed based on the signal of characteristic ions for each particular triorgano-tin compound. The detection limits of the set of the above four triorgano-tin species were ranged between 13 – 45 pg as absolute mass of Sn injected into the column and the relative standard deviation was ranged between 4.3 – 9.9 %. Finally, the performance characteristics of the method were compared to those reported in literature using similar tandem LC-MS techniques.
Export Options
About this article
Cite this article as:
M. Tzollas N., A. Zachariadis G. and Rosenberg E., Speciation Study of Trialkyl- and Triphenyl- Tin by Liquid Chromatography Using Ion Trap TOF Tandem MS and Atmospheric Pressure Chemical Ionization, Current Analytical Chemistry 2013; 9 (2) . https://dx.doi.org/10.2174/1573411011309020012
DOI https://dx.doi.org/10.2174/1573411011309020012 |
Print ISSN 1573-4110 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6727 |
Call for Papers in Thematic Issues
Advancements in biomedicine, corrosion inhibition/monitoring, and lubrication of carbon dots
Carbon dots, a class of carbon-based nanomaterials, have garnered substantial interest in various scientific and engineering fields due to their unique properties, including excellent optical properties, outstanding biocompatibility, easy preparation, good dispersity, ultrasmall size, low toxicity and environmental friendliness. This special issue of Current Analytical Chemistry aims to showcase cutting-edge ...read more
Applications of artificial intelligence in chemical analysis
Artificial intelligence (AI) has demonstrated its versatility in almost all scientific fields, especially analytical chemistry, which is leading the way in the integration of AI. According to Chemical Abstract Services, one of the major disciplines contributing to AI-related publications and patents is analytical chemistry. That?s because techniques such as deep ...read more
Bioanalytical and Biosensor Technologies for Target Molecules
Bioanalytical and biosensor technologies constitute the core of detecting and sensing diverse molecules within living organisms, encompassing proteins, DNA, small molecular metabolites, and beyond. These molecules assume pivotal roles in biological processes, rendering their analysis and sensing indispensable for comprehending biological phenomena and unraveling disease mechanisms. In the current landscape ...read more
Biogeochemistry: global environmental research and management
his issue focuses on the bio-pathways of trace elements (Ni, Co, Cr, Mn, Cd, Pb, Zn and REE) in soil, plant and atmospheric systems. Specific interest in the application of phytotechnologies that utilise hyperaccumulator plants (agro/phytomining). On the basis of understanding the migration and transformation of trace elements in ecosystem, ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers